Constraint-induced movement therapy for lower extremity use in activities of daily living in people with chronic hemiparesis: multiple case study.

Lower extremity constraint-induced movement therapy (LE-CIMT) is an intensive intervention protocol recently reported to improve lower extremity use in individuals with chronic hemiparesis. To test if the LE-CIMT that uses essential CIMT components, including the transfer package and intensive task-oriented training, is a feasible and potentially effective intervention to improve the lower extremity real-world use and functional ability in a group of individuals with chronic hemiparesis. A quasi-experimental pre- and post-test design study with 12 individuals with chronic stroke and impaired ambulation skills engaged in a 10-weekday LE-CIMT. Intervention feasibility was assessed, examining the training adherence, acceptability, and safety. The lower extremity motor activity log (LE-MAL), lower extremity motor function test (LE-MFT), timed up and go (TUG) and spatiotemporal gait parameters were used as clinical outcomes. Clinical data were collected at baseline, 3-day post-CIMT protocol and 30-day follow-up assessment. At baseline, LE-MAL and LE-MFT outcomes were tested over 2-week apart to ensure a stable measurement and determine the smallest real difference (SRD) in the study sample. The LE-CIMT showed excellent adherence, acceptability and safety. Ten out of 12 participants showed improvements over SRD in LE-MAL composite score (1.2 point) and eight participants in LE-MFT adjusted scores (0.8 point) in post-CIMT and 30-day follow-ups. LE-CIMT is a feasible intervention that has the potential to promote improvements in real-world use and functional ability of the paretic lower extremity in individuals with chronic stroke.

Factors associated with social participation in Brazilian older adults with Alzheimer's disease: A correlational, cross-sectional study.

The occurrence of Alzheimer's disease (AD) can exert a negative impact in social participation in affected older adults. The purpose of this study was to investigate whether social participation in older adults with AD is associated with disease stage and cognitive function as well as the quality of life and depressive symptoms in their caregivers. A correlational, cross-sectional study was conducted in 40 older adults with AD (28 women and 12 men) and 40 caregivers (30 women and 10 men). Social participation was assessed using the 'social participation' domain of the Activities of Daily Living Questionnaire. Disease stage was determined using the Clinical Dementia Rating scale and cognitive function was assessed using Addenbrooke's Cognitive Examination. Quality of life and depressive symptoms in the caregivers were evaluated using the Quality of Life Assessment Scale on Alzheimer's Disease and Beck Depression Inventory respectively. The older adults with AD had a mean percentage of 59.4% on the social participation domain and a mean score of 49.0 for cognitive function. The caregivers had mean scores of 39.1 for quality of life and 9.9 for depressive symptoms. The stepwise backward multiple linear regression model indicated that the predictors analysed together explained 48% of the variability in social participation among older adults with AD. Therefore, lower social participation among older adults with AD is associated with more advanced stages of the disease and cognitive decline in these individuals as well as a lower perception of quality of life and greater levels of depressive symptoms in their caregivers.