ABSTRACT
OBJECTIVE: MR imaging studies of 15 patients with documented vertebral column coccidioidomycosis infection were retrospectively reviewed to determine the MR imaging features of coccidioidal spondylitis. CONCLUSION: On MR imaging, coccidioidal spondylitis may be unifocal or multifocal. Involvement of an intervertebral disk, vertebral body marrow, and adjacent epidural and soft tissue is generally seen.
Subject(s)
Cervical Vertebrae/pathology , Coccidioidomycosis/diagnosis , Lumbar Vertebrae/pathology , Spondylitis/microbiology , Thoracic Vertebrae/pathology , Adult , Aged , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Retrospective Studies , Spondylitis/diagnosisABSTRACT
Using a 1.5-T system, we investigated the contrast in MR images of the uterus using a synthetic imaging program that was capable of producing images with TR values of 20 to 10220 ms and TE values of 1 to 511 ms. Synthetic images were calculated from images obtained on six normal women of reproductive age. The synthesized uterine images were essentially indistinguishable from acquired images with the same TR and TE parameters. Cervical and uterine anatomy could be clearly differentiated in synthetic images with a TE = 80 ms when the TR was as low as 100 ms. We conclude that the zonal anatomy of the uterus can be demonstrated using TR values that are much lower than those usually used for demonstrating uterine anatomy.
Subject(s)
Image Processing, Computer-Assisted/methods , Magnetic Resonance Imaging/methods , Uterus/anatomy & histology , Cervix Uteri/anatomy & histology , Contrast Media , Endometrium/anatomy & histology , Female , Humans , Image Enhancement/methods , Myometrium/anatomy & histologyABSTRACT
Plasma fibronectin, a glycoprotein that is a component of blood thrombi, was evaluated for the in vivo scintigraphic detection of pulmonary emboli in dogs. Fibronectin (canine or human) was labeled with either 131I or with 111In and diethylenetriaminepenta-acetic acid (DTPA) as the bifunctional chelating agent using a modification of the mixed anhydride method. The radiolabeled proteins were administered intravenously 20 to 30 minutes after the embolization of a 99mTc-labeled thrombus. The uptake of radioactivity by the embolus was monitored scintigraphically up to 24 hours. At the end of each experiment, the animal was killed and in vitro tissue counting of radioactivity was performed. Comparative study of the 131I- and 111In-labeled agent is presented with particular reference to their pharmacokinetics. The in vivo uptake of radioactivity by the emboli was limited, indicating that radiolabeled fibronectin is not a good scintigraphic agent for the detection of pulmonary emboli.
