ABSTRACT
In a series of 48 patients suffering from either nonseasonal asthma or classic migraine, a marked clinical alleviation was obtained in 33 patients by removing all cows milk protein from their diet. All patients who responded to the diet had laboratory evidence of lactase deficiency. Lactase deficiency may be a useful indicator of milk allergy in asthmatic or migrainous patients.
Subject(s)
Asthma/diet therapy , Lactose Intolerance/complications , Migraine Disorders/diet therapy , Milk Proteins/therapeutic use , Adolescent , Adult , Aged , Asthma/etiology , Female , Humans , Male , Middle Aged , Migraine Disorders/etiology , SeasonsABSTRACT
A case of thrombotic thrombocytopenic purpura with an unusual subacute course is described. Treatment was initiated after the patient had been ill for four weeks. Low-dose plasma exchange (10 ml/kg body weight per day) was associated with a sharp drop in the reticulocyte count and a transient reduction of lactate dehydrogenase activity to within the normal range. The administration of corticosteroids was followed immediately by the disappearance of neurological symptoms, and after high-dose plasma exchange (25 ml/kg body weight per day) all the symptoms of disease remitted. The remission has lasted for 10 months; we suggest that each of the therapeutic measures employed played a role.