ABSTRACT
INTRODUCTION: It is likely that lead poisoning via drinking water is often overlooked because of its supposed rarity and nonspecific early symptoms, which result in delayed management. EXEGESIS: One case of severe lead poisoning via drinking water is reported. The diagnosis was long missed and a particularly long chelating treatment was required. The clinical features included lead colic, a Burton's lead line, anemia, polyneuritis and arterial hypertension. Eighteen courses of calcium EDTA were required to obtain 'biological recovery'. The poisoning was linked to a very long water supply lead pipe and potomania secondary to alcohol withdrawal. CONCLUSION: This case report illustrates how difficult the early recognition of lead poisoning can be, and underlines the need to inquire about a toxic aetiology, particularly via the environment, of otherwise unexplained pathological conditions.
Subject(s)
Lead Poisoning/etiology , Lead , Water Pollution, Chemical , Water Supply , Chelating Agents/therapeutic use , Edetic Acid/therapeutic use , Humans , Lead/blood , Lead/urine , Lead Poisoning/complications , Lead Poisoning/diagnosis , Lead Poisoning/therapy , Male , Middle Aged , Porphyrias/complications , Porphyrias/diagnosisABSTRACT
Trichinellosis is an uncommon condition that is nevertheless a continuing problem as shown by two recent outbreaks in our region. The clinical features are reviewed briefly. The physical and laboratory test findings in the 117 patients affected during the first outbreak (February 1998) are reported, as well as the methods used to treat these patients.
Subject(s)
Albendazole/therapeutic use , Anthelmintics/therapeutic use , Disease Outbreaks , Trichinellosis/epidemiology , Adrenal Cortex Hormones/therapeutic use , Diagnosis, Differential , France/epidemiology , Humans , Trichinellosis/diagnosis , Trichinellosis/drug therapy , Trichinellosis/physiopathologyABSTRACT
Se conoce por historia que la población boliviana es una mezcla de Amerindios y españoles, denominados mestizos. El presente estudio se realizó para determinar la distribución de las moléculas HLA en esta población. Una muestra de 119 individuos fué tipificada por serología para HLA. El análisis de las frecuencias de especificidades serológicas HLA y haplotípicas obtenidas, junto con el delta del desequilibrio de ligamiento, mostraron que, la distribución de los genes HLA en esta población provienen de Amerindios (p>0.1) en mayor proporción, asiáticos (p<0.01) y españoles caucasoides (p<0.001) en proporciones menores. Moléculas HLA características de población negroide no pudieron ser evidenciadas (p<0.0001). Nuestros resultados añaden evidencia a la hipótesis histórica de que con la llegada de españoles a América 500 añós atrás, la mezcla ha originado una población mestiza con características particulares. El reconocimiento de estos parámetros, podría permitir una mejor aplicación de la tecnología HLA en los campos de investigación básica, transplante de órganos, y medicina forense
Subject(s)
HLA Antigens/geneticsABSTRACT
Two outbreaks of trichinellosis in the Tarn et Garonne, département, France were reported by the departmental health autorities on 2 March 1998, to the Réseau National de Santé Publique (RNSP). An epidemiological investigation began on 3 March in order to.
ABSTRACT
Two outbreaks of trichinellosis in the Tarn et Garonne, departement, France were reported by the departmental health autorities on 2 March 1998, to the Reseau National de Sante Publique (RNSP). An epidemiological investigation began on 3 March in order to
