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Z Naturforsch C J Biosci ; 64(9-10): 615-8, 2009.
Article in English | MEDLINE | ID: mdl-19957426

ABSTRACT

3-[(1-Methylpyrrol-2-yl)methyl]-4-substituted 4,5-dihydro-1H-1,2,4-triazol-5-ones were obtained by the cyclization reaction of 1-[(1-methylpyrrol-2-yl)acetyl]-4-substituted semicarbazides in alkaline medium. The effects of the synthesized compounds of the central nervous system of mice were studied.


Subject(s)
Triazoles/pharmacology , Analgesics/pharmacology , Animals , Central Nervous System/drug effects , Drug Evaluation, Preclinical , Immobilization , Male , Mice , Psychomotor Performance/drug effects , Sleep/drug effects , Thiopental/pharmacology , Triazoles/chemistry
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