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[Isolation of pomolic acid from Chamaenerion angustifolium and evaluation of its genotoxicity by microbiological tests].
Frolova, T S; Salnikova, O I; Dudareva, T A; Kukina, T P; Synitsyna, O I.
Bioorg Khim ; 40(1): 92-8, 2014.
Article in Russian | MEDLINE | ID: mdl-25898727

ABSTRACT

Fireweed (Chamaenerion angustifolium) lipophilic constituents were investigated by GC-MS analysis. 28 aliphatic and 6 triterpenic acids were found out at first time. Pomolic acid genotoxicity and mutagenicity were analyzed by Ames test and SOS chromotest. Genotoxic and mutagenic properties of pomolic acid were not detected.


Subject(s)
Mutagenicity Tests/methods , Oleanolic Acid/analogs & derivatives , Onagraceae/chemistry , Escherichia coli/drug effects , Escherichia coli/genetics , Gas Chromatography-Mass Spectrometry , Mutagens/toxicity , Oleanolic Acid/isolation & purification , Oleanolic Acid/toxicity , SOS Response, Genetics/drug effects , Salmonella typhimurium/drug effects , Salmonella typhimurium/genetics
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