1.
Infect Immun
; 11(1): 109-12, 1975 Jan.
Article
in English
| MEDLINE
| ID: mdl-163788
ABSTRACT
Lymphocytes from individuals with laboratory evidence of prior infection with herpes simplex virus (HSV) type 1 or type 2 demonstrated transformation (av antigens. Higher stimulation indexes were obtained when lymphocytes were incubated with the homologous as compared with the heterologous antigen. Higher mean lymphocyte stimulation indexes were also demonstrated in seropositive as compared with seronegative individuals. Lymphocytes from children with HSV-1 stomatitis usually became responsive to HSV-1 antigen within 2 to 6 weeks after the onset of illness. Lymphocytes from infants with neonatal HSV-2 infection were stimulated by HSV-2 antigen.
Subject(s)
Antigens, Viral , Lymphocyte Activation , Simplexvirus/immunology , Antibodies, Viral/analysis , Cell Line , Cells, Cultured , Child, Preschool , Female , Fluorescent Antibody Technique , Herpesviridae Infections/immunology , Humans , Infant , Infant, Newborn , Lymphocytes/immunology , Neutralization Tests , Pregnancy , Stomatitis/immunology , Thymidine/metabolism , Tritium
2.
Am J Epidemiol
; 91(6): 539-46, 1970 Jun.
Article
in English
| MEDLINE
| ID: mdl-4315623
Subject(s)
Genital Diseases, Female/immunology , Herpesviridae Infections/immunology , Simplexvirus/immunology , Adolescent , Adult , Aged , Antibodies/analysis , Child , Child, Preschool , Female , Fluorescent Antibody Technique , Genitalia, Female , Humans , Infant , Male , Middle Aged , Neutralization Tests , Serotyping , Simplexvirus/classification , Socioeconomic Factors
3.
Proc Soc Exp Biol Med
; 132(1): 386-90, 1969 Oct.
Article
in English
| MEDLINE
| ID: mdl-4310177