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Bull Exp Biol Med ; 154(2): 217-9, 2012 Dec.
Article in English | MEDLINE | ID: mdl-23330129

ABSTRACT

We compared the efficacy of Impaza (antibodies against endothelial NO-synthase in ultra-low doses) and Serenoa repens on the rat model of chronic aseptic prostatic inflammation. Administration of Serenoa repens in a dose of 50 mg/kg for 1.5 months prevented the development of prostate sclerosis and increased luminal area, but did delay the development of atrophic processes. In animals treated with Impaza (3 ml/kg for 1.5 months), atrophic changes in the prostate gland were practically absent. These findings indicate that Impaza can be used in complex therapy of abacterial prostatitis.


Subject(s)
Antibodies/therapeutic use , Prostatitis/drug therapy , Animals , Erectile Dysfunction , Male , Nitric Oxide Synthase Type III/metabolism , Plant Extracts/therapeutic use , Prostatitis/metabolism , Rats , Serenoa/chemistry
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