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1.
Theriogenology ; 18(4): 423-9, 1982 Oct.
Article in English | MEDLINE | ID: mdl-16725764

ABSTRACT

Serum alkaline phosphatase (AKP) and lactic dehydrogenase (LDH) activities were determined for 15 cows with retained fetal membranes (RFM) and 15 cows without retained fetal membranes (WRFM). The results revealed that the levels of both AKP and LDH were significantly higher in cows with RFM during late gestation and continued to be higher until 5th day postpartum. The usefulness of these findings for the prediction of RFM before parturition and for evaluating the therapeutic response of RFM is discussed.

2.
Theriogenology ; 15(5): 501-4, 1981 May.
Article in English | MEDLINE | ID: mdl-16725611

ABSTRACT

The comparison of external and internal, pelvimetry measurement was performed on 79, buffalo heifers, and a high, positive correlation (r=0.90) between the two methods was revealed. The pelvic area of the buffalo heifers increased progressively with the advancing age and with the increase in body weight. The convenience with which external pelvimetry could be performed, the simplicity of the equipment which was used and the accuracy of the method would certainly favor the application of external pelvimetry for routine use.

3.
Theriogenology ; 13(2): 123-6, 1980 Feb.
Article in English | MEDLINE | ID: mdl-16725484

ABSTRACT

The effectiveness of 'Fertivet' (180 mg. Cisclomiphene Citrate and 120 mg. Transclomiphene citrate mixture) in the induction of estrus and fertility was tested on sixteen anestrous cows. Of all the animals treated 14 (97.5%) expressed estrus and 8 (57.1%) conceived. Among the three breeds of cows treated, 5 out of 5 Brown Swiss, 4 out of 5 Jersey cross breeds and 5 out of 6 Sahiwal (Zebu) cows expressed estrus. These results indicate the usefulness of 'Fertivet' in the induction of fertile estrus in cows.

7.
Contraception ; 7(1): 27-45, 1973 Jan.
Article in English | MEDLINE | ID: mdl-4134033

ABSTRACT

PIP: The half-life and metabolic clearance rate of chlormadinone acetate were computed after a single iv injection of 60 to 90 mcCi 1-alpha-tritiated-chlormadinone acetate (specific activity 222 mcCi/mg) into 7 women aged 34-52 years. Plasma was extracted with acetone:MeOH for total radioactivity; then extracted with water and ether for free steroid radioactivity; then with n-butanol for conjugated steroid radioactivity; and finally extracted with chloroform:MeOH and chromatographed on thin layer with ether:benzene for specific radioactivity due to chlormadinone acetate. Blood samples were taken at .25, .5, 1, 8, 24 hours and every 24 hours for 5 days. The mean half-life of radioactivity specifically indentified as chlormadinone acetate for the first 24 hours was 2.6 hours, and after 24 hours was 81.8 hours, calculated by TAIT and BURSTEIN's method. All 4 curves, total radioactivity, conjugated steroids, free steroids, and specific activity had the same biphasic form: a rapid loss for about 24 hours, and an approaching equilibrium after 24 hours. The metabolic clearance rate was 42.61 liters per day, comparable to lynestrenol (15-30 liters) and norethynodrel. The half-life is much longer than that of progesterone (.96 and 10.7 minutes), estradiol (20 and 70 minutes), and norethynodrel (76 minutes and 45 hours). These data generate an estimate of the concentration of chlormadinone acetate in plasma of women taking .5 mg daily: about .45 ng/ml, i.e. about one-thirteenth the concentration of progesterone.^ieng


Subject(s)
Fertility/drug effects , Adult , Chlormadinone Acetate/blood , Chlormadinone Acetate/pharmacology , Chromatography, Thin Layer , Female , Half-Life , Humans , Hysterectomy , Middle Aged , Time Factors , Tritium
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