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Ann Thorac Surg ; 100(5): e97-8, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26522578

ABSTRACT

Lipoblastoma is a rare fatty tumor that is diagnosed almost exclusively in children. Presentation often consists of respiratory symptoms; chest computed tomography shows a hypodense, low, attenuated mediastinal mass. Surgical approach and anesthetic management are dependent on the location of the tumor and the degree of airway compression; in most cases, a thoracotomy is performed, although a sternotomy is used in selected cases. Final diagnosis can be confirmed using molecular genetic analysis; a genetic hallmark of lipoblastoma is the rearrangement of chromosomal region 8q12 and the PLAG1 gene. Tumor recurrence is rare when a complete resection is performed.


Subject(s)
Anesthesia, General/methods , Extracorporeal Membrane Oxygenation/methods , Lipoblastoma/surgery , Mediastinal Neoplasms/surgery , Sternotomy/methods , Biopsy , Bronchoscopy , Diagnosis, Differential , Humans , Infant , Lipoblastoma/diagnosis , Male , Mediastinal Neoplasms/diagnosis , Tomography, X-Ray Computed
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