ABSTRACT
In our study, the rate of pregnancy by transfer and puncture was not significantly different in unexplained and in tubal infertility, but the mean number of transferred embryos was significantly higher in the first group. To explain these data, we compared the quality of embryos in 32 punctures realized among 29 women with unexplained infertility and in 171 punctures planned among 156 women with tubal infertility. The percentage of embryos with 4 or more blastomeres was significantly lower in the unexplained infertility group than in the pure tubal infertility group.
Subject(s)
Blastomeres , Fallopian Tube Diseases/complications , Infertility/etiology , Infertility/therapy , Adult , Blastomeres/classification , Blastomeres/metabolism , Blastomeres/pathology , Case-Control Studies , Cleavage Stage, Ovum , Embryo Transfer/methods , Female , Humans , Male , Pregnancy , Pregnancy OutcomeABSTRACT
A comparative study of the association of mitotic acrocentric chromosomes and acrocentric bivalents at the pachytene stage shows that at least two factors can act in the associative behaviour of these chromosomes: (1) Nor activity and (2) the presence of satellite DNA in the short arms of these chromosomes. These factors do not act with the same intensity in the two cell lines studied. In lymphocytes, Nor activity prevails, whereas satellite DNA plays the main role in the association of acrocentric chromosomes in germ cells at the pachytene stage.
