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Pediatriia ; (2): 36-40, 1990.
Article in Russian | MEDLINE | ID: mdl-2349037

ABSTRACT

Xydofon was applied to the treatment of 68 children suffering from different renal diseases associated with metabolic disorders. The latter ones involved oxaluria (28 children), uraturia (17 children), cystinuria (14 children), and phosphaturia (9 children). To appraise the action of xydofon, use was made of the indicators of membranolysis, cellular homeostasis of calcium, lipid peroxidation, and of the level of beta 2-microglobulin in urine. The results obtained indicate that xydofon can be used as an effective remedy for the treatment of children suffering from nephropathies associated with metabolic disorders.


Subject(s)
Calcium Metabolism Disorders/drug therapy , Cystinuria/drug therapy , Diphosphonates/therapeutic use , Hyperoxaluria/drug therapy , Kidney Diseases/drug therapy , Kidney/drug effects , Adolescent , Calcium Metabolism Disorders/etiology , Calcium Metabolism Disorders/prevention & control , Child , Child, Preschool , Cystinuria/etiology , Cystinuria/prevention & control , Diphosphonates/administration & dosage , Etidronic Acid , Humans , Hyperoxaluria/etiology , Hyperoxaluria/prevention & control , Kidney/metabolism , Kidney Diseases/metabolism , Kidney Diseases/prevention & control , Uric Acid/urine
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