ABSTRACT
The authors conclude that breakdown of long-term cerebral adaptation to prolonged occupational hazards manifests itself as various types of disordered relationships between brain hemispheres. Evidence is that value and direction of changes in coherence (interrelationship) of EEG rhythms between symmetrical zones of brain cortex, spatial distribution of these changes, although lacking strict specificity, reflect stress phenomena in higher divisions of CNS and are interesting for solving problems of occupational conditionality of general unfavorable reactions in the system.
Subject(s)
Brain/drug effects , Electroencephalography , Functional Laterality/drug effects , Hazardous Substances/adverse effects , Occupational Diseases/chemically induced , Occupational Diseases/diagnosis , Occupational Exposure/adverse effects , Solvents/adverse effects , Adaptation, Physiological/physiology , Adult , Female , Humans , Male , Severity of Illness IndexSubject(s)
Neurotic Disorders/diagnosis , Neurotic Disorders/etiology , Occupational Diseases/diagnosis , Occupational Diseases/etiology , Occupational Exposure/adverse effects , Adult , Brain/physiopathology , Chronic Disease , Electroencephalography , Female , Humans , Industry , Male , Neurotic Disorders/physiopathology , Occupational Diseases/physiopathology , Time FactorsABSTRACT
The study covered informative and diagnostic value of parameters in EEG spectral coherent analysis for early and differential diagnosis of chronic exposure to organic solvents. Neurotic symptoms appeared to be early signs of the toxic effect and to be associated with dramatic decrease in regulatory influence from thalamic and hypothalamic structures.
Subject(s)
Brain/drug effects , Electroencephalography/methods , Functional Laterality/drug effects , Occupational Diseases/chemically induced , Occupational Diseases/diagnosis , Occupations , Solvents/adverse effects , Adult , Computing Methodologies , Female , Humans , Occupational Diseases/epidemiologyABSTRACT
The authors studied value of laboratory CNS tests in early diagnosis of chronic exposure to organic solvents. The tests include quantitative and qualitative evaluation of personal profile, higher psychic functions and bioelectric activity of brain. Findings are objective parameters of early CNS response to solvents--EEG signs characteristic for hypothalamic irritation, moderate diffuse increase in MMPI personal profile with secondary neurotic type and marked disorder of attention that is considerably influenced by nonspecific activating system of brain.