ABSTRACT
A preparation commonly used as a local anesthetic in dentistry has been studied for the presence of antimicrobial activity. The solution, 2% Xylocaine®, with 1:100,000 epinephrine, was shown to inhibit the growth of certain organisms and to be cidal to others. Its cidal activity was significantly less than that of 2% Xylocaine without epinephrine (p < .05). Both solutions demonstrated statistically significant cidal activity when compared to controls (p < .005).
Subject(s)
Anesthesia, Dental , Bacteria/drug effects , Epinephrine/pharmacology , Lidocaine/pharmacology , Anesthesia, Local , Evaluation Studies as Topic , In Vitro TechniquesABSTRACT
An example of palatal necrotizing sialometaplasia is presented, and the clinical and microscopic features suggestive of squamous-cell carcinoma and mucoepidermal carcinoma are noted. The patient's health status, as shown by a rather thorough work-up, was unremarkable during the period which would seem to preclude a systemic etiology of this disease. The resolution of the lesion with minimal therapy is documented.
