Study on the correlation between maternal serum uric acid and foetal birth weight in Naqu, Tibet.

In high-altitude regions, low birth weight is mainly caused by hypoxia. We aimed to determine whether maternal serum uric acid (SUC) level was associated with decreased foetal birth weight. The relevant data of individual pregnant women who delivered between 37 and 40 weeks in the People's Hospital of Naqu City, Tibet were retrospectively collected. The correlation between maternal SUC and birth weight was examined using multivariate linear regression analysis and subgroup analysis. The results showed that there was a significant negative correlation between SUC and birth weight in pregnant women with proteinuria, female foetuses, and primiparas. Fitting smoothing curve analysis showed that there was a negative linear correlation between SUC and birth weight in primiparas and female foetuses. Maternal SUC is negatively associated with foetal birth weight in a single pregnancy with proteinuria, primipara, or female foetuses in the Naqu region of Tibet, China.IMPACT STATEMENTWhat is already known on this subject? Preeclampsia associated with hyperuricaemia can affect foetal birth weight, foetal birth weight in plains area is negatively correlated with maternal hyperuricaemia.What do the results of this study add? Maternal SUC was negatively correlated with foetal birth weight, especially in primipara, mothers with proteinuria, and pregnant girls.What are the implications of these findings for clinical practice and/or further research? The results suggest that attention should be paid to SUC in pregnant women, especially in primipara, mothers with proteinuria, and pregnant girls, in the prevention of low birth weight infants in Naqu Plateau area of Tibet.

The present situation of malnutrition and the influence factors of infants hospitalized in People′s Hospital in Naqu district,Tibet autonomous region / 中国小儿急救医学

Objective To study the nutritional status and influencing factors of children aged 1-36 months in Naqu People′s Hospital of Tibet Autonomous Region of China,and to provide reference for further improvement of their physical quality and health level.Methods The infants and young children hospitalized from January 2015 to December 2016 were enrolled in the study.The basic information were collected,which included gender,age,weight,height,diseases,feeding patterns,adding supplementary time,etc.The Z-score of the indicators for the growth and development of children recommended by WHO were evaluated,and the children′s malnutrition status and its influencing factors were analyzed.Results A total of 1 371 infants were included in the study,which included 753 male infants and 618 females,with a ratio of 1.2 to 1.The rates of growth retardation,low weight and weight loss were 25.31%(347 cases),18.75%(257 cases) and 6.13%(84 cases),respectively.There was no significant difference in the incidence of growth retardation,low body weight and weight loss among infants and young children with different months of age (1 to 6 months,7 to 12 months,13 to 24 months,25 to 36 months).The feeding mode and the time of addition of the supplemen-tary food (tsamba paste) had a significant effect on the incidence of malnutrition in infants less than 6 months old.The incidence of malnutrition in infants with exclusive breastfeeding was lowest (28.88%,93/322).The earlier the tsamba paste was added,the higher the incidence of malnutrition.Conclusion The in-cidence of malnutrition in infants and young children in Naqu People′s Hospital is high.Correct feeding con-cept should be paid attention to.Early breastfeeding and adding supplementary food rationally for infants and young children are very important,which is beneficial to promote their nutritional status and improve the health.