ABSTRACT
The incidence of definite hypertension increases with advancement of age, and one third of the elderly population is affected. Isolated systolic hypertension is frequent in this population (10 to 12 percent in subjects between 65 and 74 years of age). The role of hypertension as a cardiovascular risk factor has been confirmed in the elderly population by the increase in cerebrovascular accidents, and by the incidence of myocardial infarction with the rise in blood pressure. The relationship between elevated diastolic and systolic blood pressure and mortality rates in the elderly is also well documented (Framingham). Effective treatment of hypertension significantly reduces the risk of associated complications: cardiovascular death, congestive heart failure, and stroke. However, the goal of antihypertensive therapy in the elderly should be not only to reduce morbidity and mortality rates, but also to do so without adverse effects on the functional well-being of patients.
Subject(s)
Aging , Hypertension/epidemiology , Aged , Antihypertensive Agents/therapeutic use , Cardiovascular Diseases/epidemiology , Cardiovascular Diseases/etiology , Female , France , Humans , Hypertension/complications , Hypertension/drug therapy , Male , Middle Aged , Risk Factors , United StatesABSTRACT
The authors report 2 cases of autoimmune hemolytic anemia (AHA) and Hodgkin disease. The Hodgkin disease often precedes AHA. Most patients are found to have extensive disease; histologic features are classified as being of high grades of malignancy (mixed cellularity and nodular sclerosis types). Anti I, Rh, IgG auto antibody is commonly observed at 37 degrees C. AHA and Hodgkin disease are equally improved by chemotherapy. The prognosis and significance of this pathological association are unclear.
