ABSTRACT
Acute poststernotomy mediastinitis is a serious complication of cardiac surgery and is associated with high mortality. Conservative treatment with local debridement, irrigating-suction systems, and specific antibiotic therapy is sometimes inadequate. Omentoplasty is occasionally used for reconstruction and the treatment of various chest diseases. This useful procedure is most often indicated for suppurative processes and radionecrosis, to complement myoplasty, or to cover a chest wall prosthesis. When used to treat poststernotomy mediastinitis secondary to cardiac surgery, omentoplasty improves control of infection and prognosis. We describe 2 cases of poststernotomy mediastinitis secondary to cardiac revascularization surgery in which omentoplasty was an effective treatment. Excellent control of infection was achieved.
Subject(s)
Coronary Artery Bypass , Mediastinitis/etiology , Omentum/surgery , Postoperative Complications , Adult , Aged , Humans , Male , Mediastinitis/microbiology , Mediastinitis/surgery , Sternum/microbiology , Sternum/surgeryABSTRACT
La esternomediastinitis aguda es una complicación grave que puede aparecer tras intervenciones de cirugía cardíaca y que presenta una elevada mortalidad. El tratamiento conservador mediante curas locales, sistemas de drenaje-lavado y uso de antibióticos específicos es a veces insuficiente. La omentoplastia, ocasionalmente utilizada en la reconstrucción y tratamiento de diferentes enfermedades torácicas, es un procedimiento útil, que tiene su mayor indicación en procesos supurativos, radionecrosis, complemento a mioplastias y protección de prótesis de pared torácica. Su utilización en el tratamiento de la esternomediastinitis secundaria a cirugía cardíaca ayuda al control de la infección y mejora la evolución de los pacientes. Presentamos 2 casos de esternomediastinitis secundaria a cirugía de revascularización miocárdica en los que la omentoplastia ha sido un tratamiento efectivo, consiguiendo excelentes resultados en el control de la infección
Acute poststernotomy mediastinitis is a serious complication of cardiac surgery and is associated with high mortality. Conservative treatment with local debridement, irrigating-suction systems, and specific antibiotic therapy is sometimes inadequate. Omentoplasty is occasionally used for reconstruction and the treatment of various chest diseases. This useful procedure is most often indicated for suppurative processes and radionecrosis, to complement myoplasty, or to cover a chest wall prosthesis. When used to treat poststernotomy mediastinitis secondary to cardiac surgery, omentoplasty improves control of infection and prognosis. We describe 2 cases of poststernotomy mediastinitis secondary to cardiac revascularization surgery in which omentoplasty was an effective treatment. Excellent control of infection was achieved
Subject(s)
Humans , Adult , Aged , Omentum/surgery , Mediastinitis/surgery , Myocardial Revascularization/adverse effects , Mediastinitis/etiology , Postoperative Complications/surgeryABSTRACT
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Subject(s)
Male , Female , Adult , Humans , Postoperative Complications/diagnosis , Postoperative Complications/epidemiology , Fistula/complications , Respiratory Tract Fistula/complications , Respiratory Insufficiency/complications , Pneumonectomy/methods , Sensitivity and Specificity , Respiratory Distress Syndrome/complications , Respiratory Distress Syndrome/diagnosis , Respiratory Distress Syndrome/therapy , Empyema/complications , Respiratory Tract Fistula/diagnosis , Empyema/diagnosis , Respiratory Distress Syndrome/epidemiology , Respiratory Distress Syndrome/mortality , Respiratory Distress Syndrome/physiopathologyABSTRACT
OBJECTIVE: To evaluate the effect of comorbidity as an independent prognostic factor in lung cancer. METHOD: Data on 2991 consecutive cases of lung cancer were collected prospectively from 19 Spanish hospitals between 1993 and 1997 by the Bronchogenic Carcinoma Cooperative Group of the Spanish Society of Pneumology and Thoracic Surgery (GCCB-S). To evaluate the effect of comorbidity on survival, 1121 patients with non-small cell lung cancer (NSCLC) in pathological stage I who underwent complete resection were selected, excluding operative mortality. The presence of specific comorbidities at the time of thoracotomy was registered prospectively. RESULTS: Cox regression analysis showed that tumour size (0-2, 2-4, 4-7, >7 cm) (HR 1.45 95% CI 1.08 to 1.95), 1.86 (95% CI 1.38 to 2.51), 2.84 (95% CI 1.98 to 4.08)), the presence of a previous tumour (HR 1.45 (95% CI 1.17 to 1.79)) and age (HR 1.02 (95% CI 1.01 to 1.03)) had a significant prognostic association with survival. This study excluded the presence of visceral pleural involvement or other comorbidities as independent variables. CONCLUSION: The presence of a previous tumour is an independent prognostic factor in pathological stage I NSCLC with complete resection, increasing the probability of death by 1.5 times at 5 years. It is independent of other comorbidities, TNM classification and age.
Subject(s)
Carcinoma, Non-Small-Cell Lung , Lung Neoplasms , Neoplasms, Second Primary , Adult , Aged , Aged, 80 and over , Carcinoma, Non-Small-Cell Lung/mortality , Carcinoma, Non-Small-Cell Lung/pathology , Carcinoma, Non-Small-Cell Lung/surgery , Cause of Death , Comorbidity , Female , Humans , Lung Neoplasms/mortality , Lung Neoplasms/pathology , Lung Neoplasms/surgery , Male , Middle Aged , Prognosis , Prospective Studies , Risk Factors , SpainABSTRACT
INTRODUCTION: Since 1974, a tumor size of 3 cm in diameter has been regarded as the prognostic threshold in the staging of bronchogenic carcinoma. OBJECTIVE: To study the prognostic behavior of surgical-pathologic tumor size in non-small cell lung cancer (NSCLC) with complete resection. DESIGN: Four-year multi-institutional prospective study from 1993 to 1997. PATIENTS: Consecutive cases of NSCLC in pathologic stages IA-IB (pIA-pIB) treated surgically with complete resection in hospitals belonging to the Bronchogenic Carcinoma Co-operative Group of the Spanish Society of Pneumology and Thoracic Surgery (GCCB-S). METHODS: The Schoenfeld procedure was used to identify different prognostic groups, considering 1 cm as the measurement unit. RESULTS: Based on the 1,020 cases evaluated, four prognostic groups were identified: 0 to 2 cm (group A; n = 147), 2.1 to 4 cm (group B; n = 448), 4.1 to 7 cm (group C; n = 336), and > 7 cm (group D; n = 89). At 5 years, survival was 0.63 (95% confidence interval [CI], 0.58 to 0.68), 0.56 (95% CI, 0.53 to 0.59), 0.49 (95% CI, 0.46 to 0.52), and 0.38 (95% CI, 0.32 to 0.44) for groups A, B, C, and D, respectively. Differences between paired groups (log-rank) were significant: 0.0074 between groups A and B, 0.0048 between groups B and C, and 0.0034 between groups C and D. CONCLUSIONS: In initial stages (pIA-pIB) of NSCLC, the 3-cm value was not found to behave as a prognostic threshold; in this study, four surgical-pathologic tumor size groups were identified with strong prognostic differences: from 0 to 2 cm, from 2.1 to 4 cm, from 4.1 to 7 cm, and > 7 cm.
