Three-dimensional reconstruction of the hand from biplanar X-rays: Assessment of accuracy and reliability.

BACKGROUND: Functional disorders of the hand are generally investigated first using conventional radiographic imaging. However, X-rays (two-dimensional (2D)) provide limited information and the information may be reduced by overlapping bones and projection bias. This work presents a three-dimensional (3D) hand reconstruction method from biplanar X-rays. METHOD: This approach consists of the deformation of a generic hand model on biplanar X-rays by manual and automatic processes. The reference examination being the manual CT segmentation, the precision of the method was evaluated by a comparison between the reconstructions from biplanar X-rays and the corresponding reconstructions from the CT scan (0.3mm section thickness). To assess the reproducibility of the method, 6 healthy hands (6 subjects, 3 left, 3 men) were considered. Two operators repeated each reconstruction from biplanar X-rays three times to study inter- and intra-operator variability. Three anatomical parameters that could be calculated automatically from the reconstructions were considered from the bone surfaces: the length of the scaphoid, the depth of the distal end of the radius and the height of the trapezius. RESULTS: Double the root mean square error (2 Root Mean Square, 2RMS) at the point/area difference between biplanar X-rays and computed tomography reconstructions ranged from 0.46mm for the distal phalanges to 1.55mm for the bones of the distal carpals. The inter-intra-observer variability showed precision with a 95% confidence interval of less than 1.32mm for the anatomical parameters, and 2.12mm for the bone centroids. DISCUSSION: The current method allows to obtain an accurate 3D reconstruction of the hand and wrist compared to the traditional segmented CT scan. By improving the automation of the method, objective information about the position of the bones in space could be obtained quickly. The value of this method lies in the early diagnosis of certain ligament pathologies (carpal instability) and it also has implications for surgical planning and personalized finite element modeling. LEVEL OF PROOF: Basic sciences.

Multivariable passive ankle impedance in stroke patients: A preliminary study.

Multivariable ankle mechanical impedance was estimated in four stroke survivors, in coupled dorsi- plantarflexion and inversion-eversion. We applied external torque perturbation with an ankle robot and used multi-input, multi-output stochastic system identification methods to estimate impedance, in both paretic and nonparetic limbs. Subjects were instructed to remain at rest throughout the four trials performed on each leg. Impedance projected onto the directions of maximum and minimum stiffness was fit to a 2nd order linear model, including inertia, viscosity and stiffness. For most trials, stiffness and damping in dorsi-plantarflexion are increased on the paretic side. However, for two subjects, overall impedance is not increased in the absence of sustained involuntary tonic contraction, registering values comparable to the non-paretic side. Thus, we speculate that the intrinsic properties of the paretic ankle remained unaffected at the evaluated pose. Spasticity (hyperflexive stretch reflex) would have systematically increased stiffness and damping, even in the absence of involuntary contraction. Hence, we speculate that these two subjects did not exhibit spasticity, while the remaining two subjects did, since impedance was increased, with no involuntary tonic muscle contraction. Regarding inversion-eversion, impedance in this direction remained unaffected by stroke. We evaluated two volunteers before and after the application of botulinum toxin. Surprisingly, ankle stiffness was not reduced, but anisotropy was normalized.

Scapholunate kinematics after flexible anchor repair.

The scapholunate joint is one of the keystones of the wrist kinematics, and its study is difficult due to the carpal bones size and the richness of surrounding ligaments. We propose a new method of quantitative assessment of scapholunate kinematics through bone motion tracking in order to investigate scapholunate ligament lesion as well as repair techniques. On 6 intact wrists, steel beads were inserted into the bones of interest to track their motions. Experimental set up allowed wrist flexion extension and radio-ulnar deviation motions. Low-dose bi-planar radiographs were performed each 10° of movement for different configurations: 1) intact wrist, 2) scapholunate ligament division, 3) repair by soft anchors at the posterior then 4) anterior part. Beads' 3D coordinates were computed at each position from biplanar X-Rays, allowing accurate registration of each wrist bone. The Monte Carlo sensitivity study showed accuracy between 0.2° and 1.6 ° for the scaphoid and the lunate in motions studied. The maximum flexion-extension range of motion of the scaphoid significantly decreased after anterior repair from 73° in injured wrist to 62.7°. The proposed protocol appears robust, and the tracking allowed to quantify the anchor's influence on the wrist kinematics.

Passive Wrist Stiffness: The Influence of Handedness.

OBJECTIVE: This paper reports on the quantification of passive wrist joint stiffness and investigates the potential influence of handedness and gender on stiffness estimates. METHODS: We evaluated the torque-angle relationship during passive wrist movements in 2 degrees of freedom (into flexion-extension and radial-ulnar deviation) in 13 healthy subjects using a wrist robot. Experimental results determined intrasubject differences between dominant and nondominant wrist and intersubject differences between male and female participants. RESULTS: We found differences in the magnitude of passive stiffness of left- and right-hand dominant males and right-hand dominant females suggesting that the dominant hand tends to be stiffer than the nondominant hand. Left-hand stiffness magnitude was found to be 37% higher than the right-hand stiffness magnitude in the left-handed male group and the right-hand stiffness magnitude was 11% and 40% higher in the right-handed male and female groups, respectively. Other joint stiffness features such as the orientation and the anisotropy of wrist stiffness followed the expected pattern from previous studies. CONCLUSION: The observed difference in wrist stiffness between the dominant and nondominant limb is likely due to biomechanical adaptations to repetitive asymmetric activities (such as squash, tennis, basketball, or activities of daily living such as writing, teeth brushing, etc.). SIGNIFICANCE: Understanding and quantifying handedness influence on stiffness may have critical implication for the optimization of surgical and rehabilitative interventions.