ABSTRACT
Neuroblastoma is the most common childhood malignancy arising from the sympathetic neuroblast cells. The most common sites of origin are the adrenal glands and paravertebral regions. However, the involvement of the heart is a rare occurrence in adolescents. Here, we report a case of a 12-year-old male child who was misdiagnosed as a case of cardiac myxoma on initial presentation. Following surgical resection and histological examination, neuroblastoma was revealed. This case report highlights the differential diagnosis for the cardiac mass in an adolescent with an unknown primary origin and also the importance of tissue histopathology for the diagnosis and management of neuroblastoma.
ABSTRACT
Diabetic nephropathy (DN) is the most consequential and longstanding microvascular complication of type 1 diabetes mellitus (T1DM) and the most common cause for renal replacement therapy throughout the world. The most important risk factor for DN includes poor glycemic control. We present a rare case where biopsy-proven grade 3 DN had a concurrent presentation at the time of diagnosis of T1DM in a 12-year-old female child. This earlier than expected DN noted in this patient raises the question regarding the need for earlier surveillance for DN in children.