ABSTRACT
The convalescence phase of severe meningococcal sepsis is complicated by immune complex reactions with arthritis being the commonest. No standard guidelines exist for management of such complications, but non-steroidal anti-inflammatory drugs and steroids have been used with varying success. We report excellent response to intravenous immunoglobulin in a child with immune complex reaction following meningococcal sepsis.
Subject(s)
Immune Complex Diseases/therapy , Immunoglobulins, Intravenous/therapeutic use , Meningococcal Infections/therapy , Sepsis/therapy , Adolescent , Anti-Bacterial Agents/therapeutic use , Drug Substitution , Drug Therapy, Combination , Humans , Immune Complex Diseases/immunology , Male , Meningococcal Infections/drug therapy , Meningococcal Infections/immunology , Sepsis/drug therapy , Sepsis/immunology , Treatment OutcomeABSTRACT
OBJECTIVE: To identify cases of malaria with unusual presentations. METHODS: The medical record of all the cases of malaria admitted to PICU and pediatric general ward from Oct 2006 to Sep 2009, were reviewed and cases with unusual presentations were identified. The study design was retrospective descriptive study. RESULTS: Sixteen (10%) out of 162 malaria cases had unusual presentations - three had hemiplegia, two each with viral hepatitis-like presentation, acute abdomen, gastrointestinal bleed, generalized edema and hyperglycemia and one each with ptosis, severe headache and subacute intestinal obstruction-like presentation. Eleven cases had mixed parasitemia and two each with P. vivax and P. falciparum. One case was diagnosed on clinical grounds. CONCLUSION: Malaria is a common disease, but both typical and atypical presentations deserve attention for early diagnosis and management.
