Subject(s)
Comprehensive Health Care/organization & administration , Delivery of Health Care, Integrated/organization & administration , HIV Infections/therapy , Models, Organizational , Adolescent , Adult , Chicago , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Program Development , Referral and ConsultationABSTRACT
Given the diversity and increasing life span of HIV-positive people, medical management of the associated complications is becoming more complex. This complexity is compounded by the growing number of drugs available to treat people with HIV/AIDS. Information regarding the adverse reactions and/or interactions of these drugs in combination is limited. The purpose of this paper is to review what is currently known about synergistic, antagonistic, and potentially toxic interactions. Included is a table containing side effects and interactions among drugs commonly used to treat clients with HIV/AIDS.
Subject(s)
Drug Interactions , Drug Monitoring/nursing , Drug Therapy, Combination , HIV Infections/drug therapy , Age Factors , Anti-HIV Agents/pharmacology , Anti-HIV Agents/therapeutic use , HIV Infections/complications , HIV Infections/nursing , Humans , PharmacokineticsABSTRACT
This article is an integrative review of the research which has been carried out based on Martha Rogers' conceptual framework, the science of unitary, irreducible human beings. Results of the review supported the model and theories which have been derived from the framework. However, because of methodological difficulties in measuring the concepts and because of the instruments being used, this support is not statistically significant. More research is needed using methods and instruments which better fit the concepts that are basic to the Rogerian principles of homeodynamics. Also, theories being used as the basis of the study need to be more definitively stated in future research.