The mechanism of the replacement of aluminum atoms in 1-ethyl-3-alkylalumolanes by boron atoms with boron halides.

In this study, the mechanism of the replacement reaction of an aluminum atom by a boron atom in the 1-ethyl-3-substituted alumolanes with boron halides is proposed. Theoretical and experimental justifications based on the DFT quantum chemical calculations of the energy parameters of possible reaction routes coupled with monitoring of the reaction between 1-ethyl-3-butylalumolane and BF3·Et2O, BCl3 and BBr3 using 1H, 13C, 11B and 27Al NMR spectroscopy are provided.

Synthesis, photo and acidochromic properties of spiropyran-containing methanofullerenes.

Spiropyran-containing methanofullerenes able to rapidly and reversibly respond to optical and chemical stimuli were synthesized for the first time by the Bingel-Hirsch reaction and catalytic cycloaddition of diazo compounds to carbon clusters. The effects of substituent structure in the new hybrid molecule and the mode of spiropyran attachment to fullerene on the spectral kinetic properties and photo- and acidochromic behavior of the synthesized fullerene derivatives was established.

Photocontrolled organic field effect transistors based on the fullerene C60 and spiropyran hybrid molecule.

Photocontrolled organic field-effect transistors (OFETs) containing a hybrid compound of fullerene C60 (n-semiconductor) with spiropyran (electrical conductivity photocontroller) as the active layer were fabricated for the first time. It was found that an OFET based on the hybrid compound, unlike the multilayer transistor (a device based on unmodified fullerene C60 and spiropyran in different layers), has higher transfer characteristics (source-to-drain current), charge carrier mobility in the active layer, and response rate to external influence, which makes them promising materials for the manufacture of optical memory elements.

[Oxidation of dermatan sulfate with a NaOCl-NaBr-2,2,6,6-tetramethylpiperidine-1-oxyl reagent in the water medium].

The oxidation of primary hydroxyl groups in dermatan sulfate with the NaOCl-NaBr-2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) reagent in an aqueous alkaline environment was carried out for the first time. Modified dermatan sulfates containing hydrated aldehyde (15-50%) and carboxyl (25-100%) groups were obtained.

[Conjugation of chondroitin sulfates with amines].

Conjugation of chondroitin sulfates with pharmacologically important amines in a water medium in the presence of 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide was studied. Conjugates with amide and isoureidocarbonyl groups were synthesized.

[Chemical modification of heparin].

Heparin was modified at carboxyl groups by reaction with several pharmacologically important amino-containing compounds in aqueous medium in the presence of 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide. In dependence on the nature of the amine and the ratio of reagents, conjugates containing 36-100% amide and 0-25% isoureidocarbonyl groups were synthesized. Isoureidoarylamide groups are present, along with amide moieties, in the products of heparin modification by hydroxyl-containing aromatic amines. The conjugate of heparin with p-aminobenzoic acid contained oligomeric arylamide.