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Khirurgiia (Mosk) ; (4): 90-5, 1991 Apr.
Article in Russian | MEDLINE | ID: mdl-2062078

ABSTRACT

The article deals with clinical experience in early diagnosis of pancreatonecrosis in which enzymological methods of examination acquire importance. The most informative test in the diagnosis of fatty pancreatonecrosis is the increase of the pancreatic lipase content in blood serum, particularly in stimulation of pancreatic secretion by pancreozymin. A new Soviet-produced peptide agent--dalargin was included in the complex drug treatment of fatty pancreatonecrosis in 74 patients. With the use of dalargin as an inhibitor of the activity of pancreatic enzymes and kinins in the treatment of fatty pancreatonecrosis a marked positive effect was produced. The mortality in fatty pancreatonecrosis was 5.5%.


Subject(s)
Pancreas/pathology , Pancreatitis/pathology , Cholecystokinin , Clinical Enzyme Tests , Enkephalin, Leucine-2-Alanine/analogs & derivatives , Enkephalin, Leucine-2-Alanine/therapeutic use , Humans , Lipase/blood , Necrosis , Pancreatitis/diagnosis , Pancreatitis/therapy
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