[Optimization of urogenital chlamydiosis diagnosis in reproductive age women].

The aim of the study is to optimize laboratory diagnosis of urogenital chlamydiosis (UGH) in reproductive age women. 133 women 18-49 years old have been investigated. Colpitis were diagnosed in 43-40, 8% of patients, cervicitis and cervical pathology in 61-46,9%, PID in 59-45,4% .For diagnosis of UGH we use polymerase chain reaction (PCR) method. Results of investigation show, that analisis of urethral specimens together with cervical specimens increase the detection of Chlamydia trachomatis in 13,6%; performance of analysis in second phase of menstrual cycle increase the detection of Chlamydia trachomatis in 15,4%; use of magnitotherapy increase detection of Chlamydia trachomatis in 25%. We use magnitotherapy in cases of chronic UGC with reproductive function failure and /or suspicion of persistent form of UGH. For improvement of diagnosis of UGH in reproductive age women we recommend performing analysis taking specimens from urethra and cervix in second phase of menstrual cycle. In case of chronic UGH and /or suspicion of persistent form of UGH we recommend use of magnitotherapy and then analysis for chlamydial infection.

[The level of leukotrienes B4 and C4 in the blood serum of rats subjected to thermal burns, x-irradiation and combined radiation-thermal injuries]. / Uroven' leikotrienov B4 i C4 v syvorotke krovi krys pri termicheskom ozhoge, rentgenovskom obluchenii i kombinirovannom radiatsionno-termicheskom porazhenii.

In the present study the content of leukotrienes B4 and C4 (LTB and LTC) in rat serum was investigated. The changes in the leukotriene content after thermal burn was different from that after X-irradiation and combined effect of radiation and heat.

[Activation of arachidonic acid metabolism--a protective reaction of the body during irradiation and combined radiation-thermal damage]. / Aktivatsiia metabolizma arakhidonovoi kisloty--zashchitnaia reaktsiia organizma pri obluchenii i kombinirovannom radiatsionno-termicheskom porazhenii.

Metabolic activity of arachidonic acid cascade enzymes in rabbit polymorphonuclear leucocytes sharply rises during the first day of irradiation, decreases at the highest mortality period, and is restored at later times. The inhibitors of the activity of lipoxygenase and cyclooxygenase and the release of arachidonic acid have been shown to increase the mortality rate and to decrease the average lifetime of rats exposed to ionizing radiation and a mixture of radiation and heat.