ABSTRACT
The abnormalities of myoelectrical activity of gastrointestinal tract were detected in 80 victims with severe combined trauma. There were observed a decrease of total electrical activity and dyscoordination of electrical activity of sections of gastrointestinal tract. An application of substrate antihypoxants should normalize the indices of myoelectrical activity of gastrointestinal tract. This approach allowed elimination of imbalance of total power between superposed (the stomach, the duodenum) and other sections of gastrointestinal tract. This would remove dyscoordination contraction of the jejunum and the ileum.
Subject(s)
Flavin Mononucleotide/administration & dosage , Gastrointestinal Motility/drug effects , Inosine Diphosphate/administration & dosage , Multiple Trauma , Myoelectric Complex, Migrating/drug effects , Niacinamide/administration & dosage , Shock, Traumatic , Succinates/administration & dosage , Surgical Procedures, Operative/methods , Administration, Intravenous , Adult , Drug Combinations , Electrodiagnosis/methods , Female , Gastrointestinal Tract/physiopathology , Humans , Male , Middle Aged , Multiple Trauma/complications , Multiple Trauma/diagnosis , Multiple Trauma/mortality , Multiple Trauma/surgery , Neuroprotective Agents/administration & dosage , Preoperative Care/methods , Shock, Traumatic/diagnosis , Shock, Traumatic/etiology , Trauma Severity Indices , Treatment OutcomeABSTRACT
Actual problems of using intramedullary blocked osteosynthesis for open fractures of the shinbones and femoral bones in patients with combined injuries are considered. The most optimal terms of operative treatment were established depending on the severity of the injuries by ISS scale and on classification of injuries of the soft tissues by Gastillo-Andersen. The schemes of antibacterial prophylactics of infectious complications are proposed both during operation and at the postoperative period. Under consideration are the questions of intraoperative boring of the bone marrow canal of the shinbones and femoral bones in severe combined injuries.
