[Effect of low-energy laser irradiation of bronchial mucosa on systemic and local immunity in patients with chronic bronchitis]. / Vliianie nizkoénergeticheskogo lazernogo oblucheniiaslizistoi obolochki bronchov na sostoianie sistemnogo i mestnogo immuniteta u bol'nykh khronicheskim bronkhitom.

The effectiveness of endobronchial low-energy laser therapy was studied in 28 patients with chronic nonobstructive bronchitis concurrent with thinning of bronchial mucosa. The course of treatment made it possible to obtain positive dynamics of most parameters of immunologic reactivity in CNB patients. Systemic immunity parameters, except for the NST and concentration of circulating immune complexes, underwent essential normalization. Marked positive changes were found in the parameters characterizing functional activity of alveolar macrophages: there was a 2.5-fold increase in adhesive properties and over 1.3-fold increase in the percentage of phagocytes. The level of secretory IgA rose significantly (by 3.5 times). Hence, a manifested therapeutic effect of this therapeutic method is mainly associated with its immune-stimulating action.