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Arch Pharm (Weinheim) ; 324(1): 35-7, 1991 Jan.
Article in English | MEDLINE | ID: mdl-2043040

ABSTRACT

Cycloaddition reactions of the nitrilimines 4-6 with N-arylmaleimides 7 and acrylamide (11) yield the pyrrolopyrazole derivatives 8-10 and 2-pyrazolines 12, respectively, in excellent yield. The regioselectivity and biological activities of some of the new compounds were investigated.


Subject(s)
Anti-Bacterial Agents/chemical synthesis , Pyrazoles/chemical synthesis , Pyrroles/chemical synthesis , Anti-Bacterial Agents/pharmacology , Bacteria/drug effects , Microbial Sensitivity Tests , Pyrazoles/pharmacology , Pyrroles/pharmacology
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