ABSTRACT
A 2-yr-old female brook trout, Salvelinus fontinalis, maintained at a state fish hatchery in New York (USA) was culled from the breeding stock. At necropsy, it had a markedly enlarged kidney. On histopathological examination, lymphoblastic lymphoma was diagnosed in several organs including kidney, dorsal musculature, intestines, liver, gill, pseudobranch and ovary. Origin of the tumor was uncertain, although renal involvement could have been the primary site of development.
Subject(s)
Fish Diseases/pathology , Precursor Cell Lymphoblastic Leukemia-Lymphoma/veterinary , Trout , Animals , Female , Fisheries , Gills/pathology , Intestines/pathology , Kidney/pathology , Liver/pathology , Muscle, Skeletal/pathology , Ovary/pathology , Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathologySubject(s)
Esocidae/virology , Fish Diseases , Phylogeny , Retroviridae/classification , Retroviridae/genetics , Sarcoma/veterinary , Skin Neoplasms/veterinary , Amino Acid Sequence , Animals , Gene Products, env/biosynthesis , Gene Products, env/genetics , Genes, gag , Molecular Sequence Data , RNA-Directed DNA Polymerase/chemistry , RNA-Directed DNA Polymerase/genetics , Retroviridae/isolation & purification , Sarcoma/virology , Sequence Homology, Amino Acid , Skin Neoplasms/virology , Transcription, GeneticABSTRACT
A 13-year-old male domestic shorthair cat was found to have normocytic hypochromic regenerative anemia, lymphopenia, eosinopenia, thrombocytopenia, hyperglycemia, hyperbilirubinemia, and a prolonged activated partial thromboplastin time. Transfusions of packed RBC failed to maintain the PCV above 13% for > 8 hours. The cat was euthanatized. At necropsy, the spleen liver, lymph nodes, and bone marrow were infiltrated with malignant histiocytes undergoing erythrophagocytosis.