ABSTRACT
An 28-year-old Moroccan woman with primary infertility and OLIGO-amenorrhea was referred for hysteroscopic synechiolysis. When a diagnostic hysteroscopy was performed, a bizarre, irregular, 'cloudy' endometrium was seen. The diagnosis endometrial tuberculosis was confirmed by histological examination. Treatment with antituberculosis drug therapy resulted in a normal menstrual cycle. A normal endometrium and uterine cavity was seen at control hysteroscopy. Because of extensive irreparable tubal damage this patient will be offered IVF treatment.
Subject(s)
Amenorrhea/etiology , Infertility, Female/etiology , Tuberculosis, Female Genital/complications , Adult , Anti-Bacterial Agents , Antitubercular Agents/therapeutic use , Drug Therapy, Combination/therapeutic use , Female , Humans , Tuberculosis, Female Genital/diagnosis , Tuberculosis, Female Genital/drug therapyABSTRACT
We describe a 28-week-old fetus with severe non-immune hydrops. Intrauterine cord blood sampling revealed hypercalcaemia of 3.4 mmol/l (n = 2.6 +/- 0.1). Subsequently, a postmortem examination revealed supravalvular aortic and pulmonary artery stenosis together with extensive arterial calcification. The maternal calcium, 25-hydroxyvitamin D3, 1,25-dihydroxyvitamin D3, and parathyroid hormone levels were normal at delivery. This is the first time that hypercalcaemia has been diagnosed in utero. We speculate on the fact that the disorder resulted as a consequence of abnormal vitamin D metabolism in the fetoplacental unit, and that it might be related to the Williams syndrome.
Subject(s)
Edema/diagnosis , Fetal Diseases/diagnosis , Hypercalcemia/diagnosis , Adult , Aortic Valve Stenosis/congenital , Calcinosis/pathology , Female , Fetal Diseases/pathology , Humans , Pregnancy , Pulmonary Valve Stenosis/congenital , Syndrome , Vitamin D/metabolismSubject(s)
Adrenocorticotropic Hormone/metabolism , Calcitonin/metabolism , Carcinoma/metabolism , Thyroid Neoplasms/metabolism , Adrenocorticotropic Hormone/analysis , Adrenocorticotropic Hormone/blood , Biological Assay , Calcitonin/analysis , Calcitonin/blood , Carcinoma/pathology , Depression, Chemical , Dexamethasone , Fluorescent Antibody Technique , Humans , Hydrocortisone/blood , Male , Middle Aged , Neoplasm Metastasis , Parathyroid Hormone/blood , Radioimmunoassay , Secretory Rate , Stimulation, Chemical , Thyroid Neoplasms/pathology , VasopressinsSubject(s)
Education, Medical , Pathology/education , Teaching , Audiovisual Aids , Group Processes , Netherlands , Peer Group , Verbal BehaviorABSTRACT
The production of 0.4mu thick, full-length sections from renal tissue taken by needle biopsy is achieved by formalin and osmic acid fixation and embedding in epoxy resin as for ultramicrotomy. The marked improvement in histological clarity by using this technique is illustrated by comparison with material embedded in paraffin.
