Size of government and willingness-to-pay for environmental policy: Evidence from a cross-country survey.

Citizen support is an important precursor to climate change mitigation polices. Public opinion can shape public policy and vice versa. This paper uses the 2010 International Social Survey Programme (ISSP) Environment Module to investigate cross-national differences in support for climate policy. We introduce size of government, measured by government revenues as a share of GDP, as a new country-level factor. Our sample includes 31,511 responses from 33 countries. We use multilevel models to estimate the relationship between country-level factors and environmental policy support, conditional on a series of individual factors. Increasing the size of government by one standard deviation reduces support for environmental policy by 0.13 points on a 5-point scale. For comparison, a one standard deviation increase in GDP per capita leads to a 0.24 increase in support and a one standard deviation increase in air pollution leads to a 0.13 point increase. The implication for environmental policy is that high tax countries have an aversion to price and tax increases aimed at protecting the environment. We conclude that use of taxes for environmental policy must include clear expectations for how revenues will be recycled or how other taxes will be lowered if they are to gain widespread support.

Highly functionalized diaminocyclopentanes: A new route to potent and selective inhibitors of human O-GlcNAcase.

A new class of compounds inhibiting de-O-glycosylation of proteins has been identified. Highly substituted diaminocyclopentanes are impressively selective reversible non-transition state O-ß-N-acetyl-d-glucosaminidase (O-GlcNAcase) inhibitors. The ease of preparative access and remarkable biological activities provide highly viable leads for the development of anti-tau-phosphorylation agents with a view to eventually ameliorating Alzheimer's disease.

Exposure to global change pressures and potential impacts on ecosystem services of mountain lakes in the European Alps.

Mountain lakes are increasingly affected by global change pressures. While there is growing evidence of impacts on ecosystem functioning, few studies considered changes in ecosystem services (ES). This study aimed (1) to examine the exposure of small and natural mountain lakes in the European Alps to global change pressures and (2) to estimate potential impacts on six relevant ES considering future climate projections and potential changes in water use. For 2455 lakes, we mapped the level of exposure to global change pressures, including climate change, atmospheric nutrient deposition, and anthropogenic activities (e.g., water use). Our results indicate that more than half of the Alpine mountain lakes feature a considerable level of exposure to global change. Hotspot analysis revealed spatial clusters of lakes with above-average exposure (23.7% of all lakes), mostly located in the central part of the Alps, while lakes with below-average exposure level prevailed in the south-western (19.3%) and eastern parts (10.6%). For 15 case study lakes, we quantified potential impacts on six key ES. The results revealed, in particular, potential negative effects on maintaining habitat and populations as well as aesthetic value, but contrastingly, also some positive effects for outdoor recreation, research and education. Our findings suggest the need for a comprehensive integration of mountain lakes into current management and policy frameworks to ensure the ecological integrity and ES provision of mountain lakes. Interdisciplinary mountain lake research will be important to overcome uncertainties related to the coupling of limnological parameters and ES indicators.