ABSTRACT
A prospective study in 76 newborn with perinatal asphyxia searching for myocardial ischemia was carried out. The disease was found in 51% of the patients. With electrocardiogram, myocardial enzymes, X ray and clinical manifestations the diagnosis was elaborated. No difference in the sex was present, the mean of gestational age was 35 weeks, and with mean birth weight 2,216 g, respiratory distress was present in all the people; only 20.5% developed heart failure and two had heart murmurs; 61.5% showed cardiomegaly. The creatine kinase MB isoenzyme at twelve hours after birth was raised in most of the patients. Respiratory distress syndrome was the principal diagnosis in 38%; hypoxic ischemic encephalopathy and peri-intraventricular hemorrhage was present in 50 and 33% of the patients, respectively. Mortality rate was 33%. Also a comparative study in the infants with and without myocardial ischemia was carried out appearing significative difference in: 1. Cardiomegaly, 2. Hypoxic-ischemic encephalopathy and 3. Creatine kinase MB isoenzyme.
Subject(s)
Asphyxia Neonatorum/complications , Cardiomyopathies/etiology , Coronary Disease/etiology , Asphyxia Neonatorum/enzymology , Cardiomyopathies/enzymology , Cardiomyopathies/physiopathology , Coronary Disease/enzymology , Coronary Disease/physiopathology , Creatine Kinase/blood , Female , Humans , Infant, Newborn , Isoenzymes , Male , Prospective Studies , Risk FactorsSubject(s)
Sepsis/etiology , Birth Weight , Delivery, Obstetric , Female , Humans , Infant, Newborn , Infant, Premature , Intensive Care Units, Neonatal , Male , Risk Factors , Sepsis/microbiologySubject(s)
Duodenal Obstruction/congenital , Intestinal Atresia/complications , Mediastinal Emphysema/etiology , Pneumothorax/complications , Diagnosis, Differential , Humans , Infant, Newborn , Male , Mediastinal Emphysema/diagnostic imaging , Pneumothorax/diagnosis , Radiography , Stomach Rupture/diagnosisABSTRACT
The presence of macro or microscopic blood in the stools of 300 premature babies was studied prospectively in relation with the future risk of necrotizing enterocolitis (NEC). The microscopic blood was investigated using the bililabstix reactive stripe. Four group were made up: group A babies, with no blood in their stools. Group B babies with microscopic blood in feces. Group C babies with macroscopic or gross blood and group D babies with initially microscopic and later gross blood in their feces. The frequency of NEC for these groups were as follows: group A 0.0%, group B 0.47%, group C 63.3% and group D 89.6%. We conclude that it is possible to predict absence of manifestations of NEC when a premature baby does not show gross blood in the stools during the first 21 days of life. When the babies show gross blood in the feces, the frequency of NEC is 63.3% and the higher frequency (89.6%), belongs to the babies with initially microscopic and later gross blood.
