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1.
Neurology ; 71(10): 731-5, 2008 Sep 02.
Article in English | MEDLINE | ID: mdl-18550859

ABSTRACT

BACKGROUND: Mexican Americans (MAs) comprise the largest component of the largest minority group within the United States. The purpose of this study was to examine ethnic and gender differences in the epidemiology, presentation, and outcomes after subarachnoid hemorrhage (SAH) in a representative United States community. Targeted public health interventions are dependent on accurate assessments of groups at highest disease risk. METHODS: All patients with nontraumatic SAH older than 44 years were prospectively identified from January 1, 2000, to December 31, 2006, as part of the Brain Attack Surveillance In Corpus Christi project, an urban population-based study in southeast Texas. Risk ratios for cumulative SAH incidence comparing MAs with non Hispanic whites (NHWs) and women with men were calculated. Descriptive statistics for other clinical and demographic variables were computed overall, by gender, and by ethnicity. RESULTS: A total of 107 patients had a SAH during the time period (7-year cumulative incidence: 11/10,000); of these, 43 were NHW (40% of cases vs 53% of the population) and 64 were MA (60% of cases vs 48% of the population). The overall age-adjusted risk ratio for SAH in MAs compared with NHWs was 1.67 (95% CI: 1.13, 2.47), and in women compared to men was 1.74 (95% CI 1.16, 2.62). Overall in-hospital mortality was 32.2%. No ethnic difference was observed for discharge disability or in-hospital mortality. CONCLUSIONS: Subarachnoid hemorrhage disproportionately affects Mexican Americans and women. Public health interventions should target these groups to reduce the impact of this severe disease.


Subject(s)
Ethnicity/statistics & numerical data , Sex Characteristics , Subarachnoid Hemorrhage/ethnology , Subarachnoid Hemorrhage/epidemiology , Age Factors , Aged , Aged, 80 and over , Female , Glasgow Coma Scale , Humans , Incidence , Latin America , Longitudinal Studies , Male , Middle Aged , Population Surveillance , Regression Analysis , Retrospective Studies , Risk Factors , White People
2.
J Neurol Neurosurg Psychiatry ; 77(3): 340-4, 2006 Mar.
Article in English | MEDLINE | ID: mdl-16484640

ABSTRACT

BACKGROUND: Studies on intracerebral haemorrhage (ICH) from tertiary care centres may not be an accurate representation of the true spectrum of disease presentation. OBJECTIVE: To describe the clinical and imaging presentation of ICH in a community devoid of the referral bias of an academic medical centre; and to investigate factors associated with lower Glasgow coma scale (GCS) score at presentation, as GCS is crucial to early clinical decision making. METHODS: The study formed part of the BASIC project (Brain Attack Surveillance in Corpus Christi), a population based stroke surveillance study in a bi-ethnic Texas community. Cases of first non-traumatic ICH were identified from years 2000 to 2003, using active and passive surveillance. Clinical data were collected from medical records by trained abstractors, and all computed tomography (CT) scans were reviewed by a study physician. Multivariable linear regression was used to identify clinical and CT predictors of a lower GCS score. RESULTS: 260 cases of non-traumatic ICH were identified. Median ICH volume was 11 ml (interquartile range 3 to 36) with hydrocephalus noted in 45%. Median initial GCS score was 12.5 (7 to 15). Hydrocephalus score (p = 0.0014), ambient cistern effacement (p = 0.0002), ICH volume (p = 0.014), and female sex (p = 0.024) were independently associated with lower GCS score at presentation, adjusting for other variables. CONCLUSIONS: ICH has a wide range of severity at presentation. Hydrocephalus is a potentially reversible cause of a lower GCS score. Since early withdrawal of care decisions are often based on initial GCS, recognition of the important influence of hydrocephalus on GCS is warranted before withdrawal of care decisions are made.


Subject(s)
Cerebral Hemorrhage/diagnosis , Aged , Aged, 80 and over , Cerebral Hemorrhage/epidemiology , Cerebral Hemorrhage/etiology , Comorbidity , Cross-Sectional Studies , Diagnosis, Differential , Female , Glasgow Coma Scale , Hospitals, Community , Humans , Hydrocephalus/diagnosis , Hydrocephalus/epidemiology , Hydrocephalus/etiology , Male , Middle Aged , Population Surveillance , Risk Factors , Sensitivity and Specificity , Texas , Tomography, X-Ray Computed
3.
Neurology ; 66(1): 30-4, 2006 Jan 10.
Article in English | MEDLINE | ID: mdl-16401841

ABSTRACT

BACKGROUND: Mexican Americans (MAs) have higher incidence rates of intracerebral hemorrhage (ICH) than non-Hispanic whites (NHWs). The authors present clinical and imaging characteristics of ICH in MAs and NHWs in a population-based study. METHODS: This work is part of the Brain Attack Surveillance in Corpus Christi (BASIC) project. Cases of nontraumatic ICH were identified from 2000 to 2003. Multivariable logistic regression was used to assess the independent associations between ethnicity and ICH location (lobar vs nonlobar) and volume (> or = 30 vs < 30 mL), adjusting for demographics and baseline clinical characteristics. Logistic regression was also used to determine the association between ethnicity and in-hospital mortality, adjusting for confounders. RESULTS: A total of 149 MAs and 111 NHWs with ICH were identified. MAs were younger (70 vs 77, p < 0.001), more often male (55% vs 42%, p = 0.04), had a lower prevalence of atrial fibrillation (2.0% vs 13%, p < 0.001), and a higher prevalence of diabetes (39% vs 19%, p < 0.001). MA ethnicity was independently associated with nonlobar hemorrhage (OR 2.08, 95% CI: 1.15, 3.70). MAs had over two times the odds of having small (< 30 mL) hemorrhages compared with NHWs (OR = 2.41, 95% CI: 1.31, 4.46). NHWs had higher in-hospital mortality, though this association was no longer significant after adjustment for ICH volume, location, age, and sex. CONCLUSIONS: There are significant differences in the characteristics of ICH in MAs and NHWs, with MA patients more likely to have smaller, nonlobar hemorrhages. These differences may be used to examine the underlying pathophysiology of ICH.


Subject(s)
Brain/blood supply , Brain/pathology , Cerebral Arteries/pathology , Cerebral Hemorrhage/complications , Cerebral Hemorrhage/ethnology , Mexican Americans/statistics & numerical data , White People/statistics & numerical data , Age of Onset , Aged , Atrial Fibrillation/epidemiology , Brain/physiopathology , Cerebral Arteries/physiopathology , Cerebral Hemorrhage/diagnosis , Cohort Studies , Comorbidity , Diabetes Mellitus/epidemiology , Female , Hospitalization/statistics & numerical data , Humans , Male , Mortality , Prevalence , Sex Distribution , Texas/epidemiology
4.
Spinal Cord ; 43(11): 684-6, 2005 Nov.
Article in English | MEDLINE | ID: mdl-15968303

ABSTRACT

STUDY DESIGN: Case report. OBJECTIVE: To report a rare complication following halo placement for cervical fracture. SETTING: United States University Teaching Hospital. CASE REPORT: A 39-year-old woman who sustained a spinal cord injury from a C6-7 fracture underwent halo placement. She subsequently developed an infection adjacent to the right posterior pin, which then became infected with Diptera larvae (maggots), necessitating removal of the pin and debridement of the wound site. CONCLUSION: Halo orthosis continues to be an effective means of immobilizing the cervical spine. Incidence of complications ranges from 6.4 to 36.0% of cases. Commonly reported complications include pin-site infection, pin penetration, pin loosening, pressure sores, nerve injury, bleeding, and head ring migration. Pin-site myiasis is rare, with no known reports found in the literature. Poor pin-site care by the patient and her failure to keep follow-up appointments after development of the initial infection likely contributed to the development of this complication.


Subject(s)
Bone Nails/adverse effects , Myiasis/etiology , Orthotic Devices/adverse effects , Adult , Animals , Diptera , Female , Humans , Infections/etiology , Spinal Cord Injuries/complications
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