1.
Anticancer Agents Med Chem
; 12(6): 611-8, 2012 Jul.
Article
in English
| MEDLINE
| ID: mdl-22263787
ABSTRACT
A series of 5-aryl-1,4-benzodiazepines with chloro- or fluoro-substituents in the second ring have been synthesized and their anti-inflammatory, myeloperoxidase and anticancer properties studied. The synthesized compounds showed potential anti-inflammatory and anticancer activities, which were enhanced in the presence of a chloro-substituent in the second ring of the 5-aryl-1,4- benzodiazepine.