ABSTRACT
Integral rheography and conjunctival biomicroscopy studied central hemodynamics (CH) and microcirculation (MC), respectively, in 37 hypertensive patients with influenza and acute respiratory viral infection (ARVI) and 38 normotensive patients with influenza and ARVI aged 41 to 94 years (group 1 and 2, respectively). In group 1 vs group 2 specific peripheral resistance was significantly higher, intravascular changes were more manifest (disseminated aggregation of red cells, slow blood flow with its incomplete block. It is shown that patients with influenza and ARVI had main functional circulatory disorders in microcirculation zone. The study of microcirculation by conjunctival biomicroscopy is important for these patients for assignment of pathogenetically sound vascular therapy, first of all disaggregants.
Subject(s)
Hypertension/complications , Hypertension/physiopathology , Influenza, Human/complications , Respiratory Tract Diseases/complications , Acute Disease , Adult , Aged , Aged, 80 and over , Female , Hemodynamics/physiology , Humans , Hypertension/diagnosis , Male , Microcirculation/physiology , Middle Aged , Respiratory Tract Diseases/virology , Severity of Illness IndexABSTRACT
AIM: To study microcirculation (MC), hemostasis (HS) and blood viscosity (BV) in influenza and acute respiratory viral infection (ARVI) in hypertensive patients. MATERIAL AND METHODS: The study group consisted of 67 hypertensive patients with influenza or ARVI. 45 influenza and ARVI normotensive subjects served control. HS and BV tests were made, conjunctival biomicroscopy was performed. RESULTS: Patients with influenza and ARVI in the acute period had distinct perivascular and vascular abnormalities, sludge phenomenon in the majority of postcapillary venules and capillaries. In convalescence microcirculation improved. HS in the acute stage of infections was characterized by fast coagulation, depression of fibrinolysis; in convalescence, a significantly enhanced platelet aggregation was seen. The highest BV occurred at low shift speeds. Hypertensive patients had higher vascular permeability and more severe intravascular changes which presented with disseminated intravascular red cell aggregation, slowing down of blood flow, its partial block. In hypertension there was also significantly higher platelet aggregation, lower disaggregation, higher BV increase in convalescence. CONCLUSION: Hypertensive patients with influenza or ARVI had serious disorders of microcirculation, HS and BV threatening cardiovascular complications in such patients.
Subject(s)
Hemostasis , Hypertension/blood , Hypertension/physiopathology , Respiratory Tract Infections/blood , Respiratory Tract Infections/physiopathology , Acute Disease , Adult , Aged , Aged, 80 and over , Blood Viscosity , Bronchitis/blood , Bronchitis/complications , Bronchitis/physiopathology , Hemorheology , Humans , Hypertension/complications , Influenza, Human/blood , Influenza, Human/complications , Influenza, Human/physiopathology , Microcirculation , Middle Aged , Respiratory Tract Infections/complications , Respiratory Tract Infections/virologyABSTRACT
Clinical and ECG findings in 186 patients with local diphtheria of the oropharynx showed that cardiac pathology in local diphtheria patients is weak and short-term. In late diagnosis and missed serotherapy myocardial damage may be more serious and eventuate to myocarditis. Premorbid background (previous infections, chronic alcohol intoxication) presents as an additional risk of myocarditis in local diphtheria.
Subject(s)
Diphtheria/diagnosis , Electrocardiography , Pharyngeal Diseases/diagnosis , Adult , Diphtheria/complications , Diphtheria/therapy , Female , Humans , Immunization, Passive , Male , Myocarditis/diagnosis , Myocarditis/etiology , Oropharynx , Pharyngeal Diseases/complications , Pharyngeal Diseases/therapy , Risk Factors , Time FactorsABSTRACT
The paper gives a review of present-day drugs effective against malaria, provides the result of a clinical trial of melloquine, fansidar, fansimeph, chlorochine in diverse malaria forms. The choice of the drug should be individual, basing on the disease severity, form and resistance of tropical malaria causative agent.
Subject(s)
Antimalarials/therapeutic use , Malaria/drug therapy , Drug Resistance , Humans , Malaria/complications , Malaria/diagnosisABSTRACT
The authors treated helminth infestation in 856 patients who have arrived to Russia from tropical countries. Early diagnosis and treatment of helminthiasis in such patients reduce their susceptibility to other diseases in the course of relevant adaptation to new climatic conditions. The authors point to high efficacy of the drugs mebendazol, albendazol, medaminol (against ancylostomiasis, ascariasis, trichocephaliasis), praziquantel (against schistosomiasis and hymenolepiasis).
