[Effect of a polysaccharide-contaning preparation from El Tor vibrions on the phagocytic activity of leukocytes and on the lysozyme titer]. / Vliianie polisakharidsoderzhashchego preparata iz vibrionov El'-Tor na fagotsitarniu aktivnost' leikotsitov i titr lizotsima

The dynamics of changes in some indices of the natural immunity of mice treated with EL-Tor vibrio preparations in doses of 50 and 500 gemma/mouse was studied. The blood for analysis was taken from the mice 24 hours, 3, 7 and 10 days after the preparation administration. The results of the study showed that administration of the polysaccharide-containing preparations from El-Tor vibrios in doses of 50 and 500 gemma/mouse was accompanied by some shifts in the regulatory mechanisms: suppression of the serum lysozyme activity on the 1st and 3rd days and its stimulation on the 7th and 10th days. The percentage of phagocytosis and its completeness increased. The indices of phagocytosis and its completeness by the respective periods decreased.

[Effect of prodigiosin on the lysozyme activity in melioidosis]. / O vliianii prodigiozana na aktivnost' lizotsima pri melioidoznoi intoksikatsii

Decreased lysozyme activity was observed under conditions of melioidosis intoxication in rats induced by intraperitoneal administration of an acetone-killed 3-day culture of the bacterial mass of the melioidosis causative agent. When prodigiozan was administered 48 hours by the 4th day which was indicative of prodigiozan activation of the factors of the microbial non-specific resistance.