[Discriminant function analysis in the assessment of laboratory test data in the correction of traditional therapy for mild icteric form of viral hepatitis B in children with food allergy].

The purpose of this investigation was to define the efficiency of inclusion of antihistamines (suprastin or tavegil), enzyme drugs (pancreatin or mesim forte) and their combinations into therapy for a mild icteric form of acute viral hepatitis B (VHB) in children with food allergy (FA). Among the examinees, there were 61 children with FA who had experienced a mild icteric form of VHB and who received traditional therapy at the age of 3-14 years. Of them, 36 children were additionally given antihistamines (n = 7), enzyme drugs (n = 20), and their combination (n = 9). About half the children (47.54%) were boys. Blood samples were biochemically tested in children for bilirubin and enzymes 1, 3, 6, 9, and 12 months after their hospital discharge. The similar laboratory tests were carried out in 20 healthy children--a comparison (control) group. Analysis of discriminant functions stated the high efficiency of inclusion of enzyme drugs, or antihistamines in particular, or their combinations with enzyme drugs, that considerably reduce the time it takes to normalize the complexes of the indices of a blood biochemical test for bilirubin and enzymes.

[Discriminant function analysis in the assessment of laboratory values in children with food allergy in acute viral hepatitis B].

The purpose of this investigation was to define the impact of food allergy (FA) in children on the time of normalization of a complex of the indices of a blood biochemical test for bilirubin and enzymes in acute viral hepatitis B (VHB). Discriminant function analysis through the mathematical expression of the combined influence of variables in a complex of the values of a blood biochemical test for bilirubin and enzymes in children with FA who had experienced a mild icteric form of VHB showed the absence of their normalization throughout one-year follow-up after hospital discharge. Among the examinees, there were twenty-five 3-14-year-old children with FA who had experienced a mild icteric form of VHB. About half of them were girls (44%). Blood biochemical tests for bilirubin and enzymes were carried out in both the acute stage of the disease and in convalescence at least 5 times 1, 3, 6, 9, and 12 months after their hospital discharge. The similar laboratory tests (blood biochemical tests for bilirubin and enzymes, marker spectrum to hepatitis virus) were performed in 20 healthy children (a control group).

[Diagnostic value of the radioimmunoassay and immunoenzyme assay in analysis of HBsAg in children with viral hepatitis]. / Diagnosticheskaia tsennost' radioimmunologicheskogo i immunofermentnogo analizov vyiavleniia HBsAg v krovi u detei, bol'nykh virusnymi gepatitami.

The purpose of the case study was to evaluate the diagnostic efficiency of radioimmunoassay (RIA) and of immune-enzyme assay (IEA) in indicating the HBsAg in the blood of children with viral hepatitis. The study was based on a simultaneous indication of HBsAg by RIA and IEA in 98 samples of blood serum (plasma). It was shown that both assays are practically univocal in as far as the HBsAg indication within the mentioned circumstances is concerned.