ABSTRACT
Inflammatory bowel disease is a chronic, lifelong disorder characterized by alternating periods of flare-ups and clinical remission. The majority of patients experience relapses several times a year. Prevention and treatment of these relapses are a major challenge to the practicing physician. Therefore, this article provides strategies that the primary care physician can use in the diagnosis and treatment of inflammatory bowel disease and prevention of relapses.
Subject(s)
Colitis, Ulcerative , Crohn Disease , Colitis, Ulcerative/drug therapy , Colitis, Ulcerative/prevention & control , Crohn Disease/drug therapy , Crohn Disease/prevention & control , Diagnosis, Differential , Humans , Primary Health CareABSTRACT
The demonstration of the pathway of enterovaginal fistulas has been challenging physicians since first described. This case demonstrates a new method for elucidating the tract pathway via flexible vaginoscopy, the use of catheters for endoscopic retrograde cholangiopancreatography, and plain films of the pelvis.
Subject(s)
Colonic Diseases/diagnosis , Colposcopy/methods , Intestinal Fistula/diagnosis , Vaginal Fistula/diagnosis , Catheterization/instrumentation , Cholangiopancreatography, Endoscopic Retrograde/instrumentation , Colposcopes , Female , Humans , Middle AgedABSTRACT
Chlorpropamide, a sulfonylurea compound used in the treatment of diabetes mellitus, type II, has been implicated as the cause of untoward reactions involving the hematopoietic, cutaneous, and gastrointestinal systems. The hepatotoxic reactions induced by this drug generally present as hepatocanalicular cholestatic reactions, in contrast to the hepatocellular reactions induced by the older sulfonylurea compounds. An unusual presentation of chlorpropamide toxicity, presenting as a mixed hepatocanalicular reaction, is reported, along with a review of the literature.
Subject(s)
Chemical and Drug Induced Liver Injury/etiology , Chlorpropamide/adverse effects , Biopsy , Chemical and Drug Induced Liver Injury/diagnosis , Chemical and Drug Induced Liver Injury/pathology , Female , Humans , Liver/pathology , Middle AgedABSTRACT
A 28-year-old woman evaluated for paresthesias, chronic diarrhea, and an enlarged thyroid gland proved to have celiac sprue and lymphocytic thyroiditis. The immunopathologic similarities of these two disorders may be more than coincidental.
Subject(s)
Celiac Disease/complications , Lymphoid Tissue/pathology , Thyroiditis/complications , Adult , Celiac Disease/immunology , Celiac Disease/pathology , Female , Humans , Thyroiditis/immunology , Thyroiditis/pathologyABSTRACT
A cervical adenocarcinoma, a left ovarian granulosa cell tumor, and a right ovarian sex cord tumor with annular tubules developed in a woman with Peutz-Jeghers syndrome. This apparent first report of three different pelvic tumors occurring in a patient with Peutz-Jeghers polyposis suggests a possible link between pelvic tumors and the Peutz-Jeghers syndrome.
