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1.
Cureus ; 16(5): e59648, 2024 May.
Article in English | MEDLINE | ID: mdl-38832147

ABSTRACT

Staphylococcus lugdunensis is a gram-positive, coagulase-negative organism, typically found in the normal skin flora, predominantly colonizing the perineal region. It has gained recognition as an opportunistic pathogen capable of causing severe infections. This manuscript presents a case study of a 75-year-old female with multiple comorbidities, including hypertension, hyperlipidemia, atrial fibrillation on Xarelto, type 2 diabetes mellitus, hypothyroidism, and a bioprosthetic aortic valve. The patient exhibited symptoms of fever, chills, and lethargy following a dog scratch that resulted in wounds on the left lower extremity. Despite initial negative findings in the drug screen and unremarkable workup for other infectious etiologies, the patient's clinical course revealed the presence of S. lugdunensis in the blood cultures. Timely intervention with broad-spectrum intravenous antibiotics and a six-week course of cefazolin led to significant improvement without recurrence. Staphylococcus lugdunensis, previously considered a relatively benign microorganism, has become a significant player in infectious diseases, particularly causing skin and soft tissue infections and infective endocarditis (IE). It is considered an aggressive pathogen, especially in chronic immunocompromised personnel, with a high potential for morbidity and mortality. S. lugdunensis was found to be the fourth most common cause of IE. The manuscript discusses the epidemiology, clinical presentation, and management of S. lugdunensis infections, emphasizing the importance of early recognition and treatment to prevent potentially fatal outcomes.

2.
Cureus ; 16(2): e53967, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38469010

ABSTRACT

We present a case of a 30-year-old male who was admitted with Streptococcus pneumoniae meningitis. He initially responded well to antibiotic therapy. However, the patient later developed symptomatic sinus bradycardia, which was likely due to intracranial hypertension. Even though the patient showed overt symptoms, vigilant monitoring, interdisciplinary collaboration, and cardiac evaluation helped avoid unnecessary interventions. This case highlights the importance of recognizing and managing rare cardiac complications associated with central nervous system infections.

3.
Cureus ; 15(12): e51069, 2023 Dec.
Article in English | MEDLINE | ID: mdl-38269221

ABSTRACT

Chest pain with focal ST elevation in the presence of elevated cardiac markers is usually believed to be secondary to an acute myocardial infarction. Moreover, widespread ST elevation is believed to be a hallmark sign of acute pericarditis. However, we present the case of a young male who presented with chest pain, elevated troponins, and focal ST elevations; however, left heart catheterization showed patent coronary arteries. The patient was treated for acute myo-pericarditis with ibuprofen and colchicine. This case illustrates the fact that focal ST elevation in a patient with chest pain and elevated markers of cardiac injury is not always secondary to an acute myocardial infarction.

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