ABSTRACT
The distribution of ABO, Rhesus blood groups and haemoglobin electrophoresis among 200 undergraduate students of Niger Delta University, Bayelsa State, Nigeria randomly selected were studied. Blood samples were collected by venepuncture from the antecubital vein. The blood sample were transferred into EDTA bottle and mixed. The determination of the ABO, Rhesus (RhD) blood groups and haemoglobin electrophoresis was done. The results showed that blood group O had the highest percentage distribution of 49% followed by blood groups A and B with 22% respectively and the least percentage distribution of 7% was blood group AB. Rh-D positive rate was 98% and it was 2% for Rh-D negative. The percentage distribution for the haemoglobin electrophoresis pattern for HbAA, HbAS, HbSS, HbAC and HbSC were 66%, 26%, 2%, 2%, and 4% respectively. HbAA and HbAS occurred more frequently than other haemoglobin variants in this study.
Subject(s)
ABO Blood-Group System , Hemoglobins/analysis , Rh-Hr Blood-Group System , Students , Universities , Adolescent , Black People/statistics & numerical data , Blood Protein Electrophoresis , Child , Female , Humans , Male , Nigeria/epidemiology , Phlebotomy , Students/statistics & numerical data , Universities/statistics & numerical data , Young AdultABSTRACT
The activity of red blood cell Glucose 6-phosphate dehydrogenase (G6PD) in one hundred and twenty six healthy male individuals who are Nigerians residing in Jos was evaluated. The enzyme activity was determined quantitatively by spectrophotometer assay method. The activity of red cell G6PD enzyme was subnormal in 20 % of the population studied. This agrees with previous report of the prevalence of G6PD deficiency in Nigerian males from the Western region of the country which is between 20 and 26 %of the population. The proportion of Nigerian males with subnormal G6PD activity is relatively constant irrespective of their geographical location.
Subject(s)
Erythrocytes/enzymology , Glucosephosphate Dehydrogenase Deficiency/epidemiology , Glucosephosphate Dehydrogenase/blood , Adult , Black People , Glucosephosphate Dehydrogenase Deficiency/enzymology , Humans , Male , Nigeria/epidemiology , Prevalence , Young AdultABSTRACT
The claim by Nigerian traditional herbal medicine practitioners that Ocimum gratissimum leaves has antidiabetic properties was investigated. Diabetes mellitus was induced with streptozotocin and graded doses of the aqueous leaf extract were administered orally to the experimentally diabetic rats for 28 days. Administration of the aqueous leaf extract caused a statistically significant reduction in plasma glucose level in streptozotocin induced diabetic rats. The extract appeared nontoxic as evidenced by normal serum levels of AST, ALT, ALP, TPT, ALB and bilirubin. These data appear to agree with claimed hypoglycaemic effects of Ocimum gratissimum.
