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Article in Russian | MEDLINE | ID: mdl-12830518

ABSTRACT

The study aimed at determination of circulating immune complexes (CIC) levels in a serum of patients with ischemic and hemorrhagic strokes, isolation of the complexes and their antigen composition identification. Spectrophotometric assay, polyethylene glycol precipitation and SDS PAG electrophoresis were used. Comparing to controls, significantly elevated levels of both small and big CIC were detected in the serum of the patients with ischemic stroke, while in the patients with hemorrhage stroke only the level of small CIC was elevated. The antigen CIC composition was specific for each stroke form and for control group either. Being compared to literature data, the results obtained revealed a specificity of the antigen CIC composition in ischemic and hemorrhagic strokes.


Subject(s)
Antigen-Antibody Complex/blood , Brain Ischemia/immunology , Intracranial Hemorrhages/immunology , Stroke/immunology , Adult , Antigen-Antibody Complex/immunology , Female , Humans , Male , Middle Aged
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