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1.
Akush Ginekol (Mosk) ; (5): 47-50, 1991 May.
Article in Russian | MEDLINE | ID: mdl-1897672

ABSTRACT

The mammary glands were examined in 36 patients with +Hyperprolactinemia-induced amenorrhea. ++Fibro-adipose transformation (33.3%), involutional changes unassociated with age (30.6%), the hyperplastic processes fibrocystic mastopathy, adenosis (36.1%) were found to be equally encountered in the pattern of breast alterations. Parlodel therapy given to patients with ++Hyperprolactinemia-induced amenorrhea not only recovers menstrual and reproductive functions, but exerts a favourable action on the mammary glands, promoting the restoration of glandular tissue and the decrease in deformity of a stromal component.


Subject(s)
Amenorrhea/etiology , Breast/pathology , Bromocriptine/therapeutic use , Fibrocystic Breast Disease/etiology , Hyperprolactinemia/complications , Adult , Amenorrhea/drug therapy , Amenorrhea/pathology , Breast/drug effects , Female , Fibrocystic Breast Disease/drug therapy , Fibrocystic Breast Disease/pathology , Humans , Hyperplasia/drug therapy , Hyperplasia/etiology , Hyperprolactinemia/drug therapy , Hyperprolactinemia/pathology
2.
Patol Fiziol Eksp Ter ; (5): 37-9, 1990.
Article in Russian | MEDLINE | ID: mdl-2293162

ABSTRACT

Energy metabolism of maternal and fetal tissues in adaptation to intermittent normobaric hypoxia was studied in experiments on 72 female Wistar rats. During pregnancy the intensity of tissue respiration in myometry was more than twice that in a nonpregnant uterus. The rate of tissue respiration in vital organs (brain) remained at a high level irrespective of exposure to the effect of a gas hypoxic mixture containing 10% oxygen, i.e. the organism of the mother and fetus provides the developing brain with an optimum amount of oxygen even in its possible deficiency. Thus, adaptation of the maternal and fetal organism to GHM-10 is attended by some shifts in energy metabolism which maintain the aerobic oxidation metabolism in the studied tissues for a long duration through more effective consumption of oxygen in its lack.


Subject(s)
Adaptation, Physiological/physiology , Energy Metabolism/physiology , Fetus/metabolism , Oxygen/physiology , Pregnancy, Animal/metabolism , Animals , Female , Pregnancy , Rats , Rats, Inbred Strains , Time Factors
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