Subject(s)
2-Aminopurine/analogs & derivatives , Acyclovir/analogs & derivatives , Amantadine/analogs & derivatives , Antiviral Agents/therapeutic use , Health Planning Guidelines , Herpes Genitalis/drug therapy , Valine/analogs & derivatives , 2-Aminopurine/therapeutic use , Acyclovir/therapeutic use , Amantadine/therapeutic use , Famciclovir , Female , Humans , Male , Military Medicine , Military Personnel , Russia/epidemiology , Valacyclovir , Valine/therapeutic useABSTRACT
In 37 patients with endosellar pituitary adenoma attended by the acromegaloid syndrome, a plasma STH level determined by a radioimmunoassay against a background of an insulin test was compared with EEG findings before and at varying time (up to 7 yrs.) after proton beam therapy using the synchrocyclotron of the Leningrad Institute of Nuclear Physics. EEG was shown to be an informative method of diagnosis of continuous pituitary adenoma growth and complications of proton beam therapy in the form of temporal paroxysms.
Subject(s)
Adenoma/physiopathology , Brain/physiopathology , Pituitary Neoplasms/physiopathology , Protons , Acromegaly/blood , Acromegaly/physiopathology , Acromegaly/radiotherapy , Adenoma/blood , Adenoma/radiotherapy , Adolescent , Adult , Brain/radiation effects , Chronic Disease , Electroencephalography , Female , Growth Hormone/blood , Humans , Male , Middle Aged , Particle Accelerators , Pituitary Neoplasms/blood , Pituitary Neoplasms/radiotherapy , Radiotherapy Dosage , Time FactorsABSTRACT
Hypothalamic disorders develop often in neurosurgical patients in the clinic. Complex study of the condition of the hypothalamic structures disclosed a relationship between the pronounced character of the disorders of the vegetative functions, changes of the EEG values according to the degree of alpha-rhythm maintenance, and the morphological changes of the hypothalamus. The results obtained can be used in working out the most adequate pathogenetic therapy.
