ABSTRACT
With the Nd:YAG laser it is possible to produce epithelial defects, fractures of Bowman's membrane or ulcer-like defects of the anterior stroma, depending on the distance, intensity, and number of optical breakdowns in front of the cornea. The histologic picture is similar to the well-known changes on the posterior surface of the cornea. The possibility of therapeutic application of the Nd:YAG laser in corneal disease is discussed.
Subject(s)
Corneal Injuries , Lasers/adverse effects , Aged , Basement Membrane/pathology , Cornea/pathology , Corneal Stroma/pathology , Corneal Ulcer/pathology , Female , HumansABSTRACT
Report on six patients with concretions in the lacrimal sac and the nasolacrimal duct. It was possible to remove the concretions in four patients by irrigation of the nasolacrimal sac with cortisone solutions. In one patient a dacryocystostomy was necessary.
Subject(s)
Calculi/diagnosis , Lacrimal Apparatus , Lacrimal Duct Obstruction/diagnosis , Nasolacrimal Duct , Adult , Aged , Female , Humans , MaleABSTRACT
An electron microscopic study was performed on eyes of Labrador dogs afflicted with progressive retinal atrophy (PRA). There was complete loss of photoreceptors, atrophy of the remaining retina and gliosis in the peripheral part while the central retina showed incomplete loss of photoreceptors and an almost total disappearance of photoreceptor outer segments. Melanin-bearing cells, largely containing melanolysosomes, were found deep inside the retina. This electron microscopic study also incorporated the retina of a middle-aged woman affected by retinopathia pigmentosa (RP). The fine structure of the diseased retina showed a similar pattern of lesions, more pronounced in the periphery of the retina. Similar electron microscopic findings between the two disease processes render PRA of the Labrador dog a useful model for a comparative study of the development and intraretinal spread of human RP.
Subject(s)
Dog Diseases/pathology , Retina/ultrastructure , Retinitis Pigmentosa/pathology , Animals , Atrophy , Dogs , Female , Humans , Middle Aged , Retina/pathology , Retinitis Pigmentosa/veterinary , Species SpecificityABSTRACT
Report on the results of immunsuppressive therapy in 6 patients with Behçet's disease. A combined regimen of azathioprine and cortisone improved the course of the disease and diminished the number of recidives. In order to prevent irreversible damage to the eye early immunosuppressive therapy is advocated. Because of possible side-effects of azathioprine the necessity of further treatment should be reevaluated after several months without symptoms and then gradually terminated.
Subject(s)
Behcet Syndrome/drug therapy , Azathioprine/pharmacology , Azathioprine/therapeutic use , Cortisone/pharmacology , Cortisone/therapeutic use , Drug Evaluation , Humans , Immunosuppressive Agents/therapeutic use , Recurrence , Time Factors , Visual Acuity/drug effectsABSTRACT
A clinicopathological report is given on a case of spontaneous chorioideal detachment in a patient with metastatic carcinoma. Histological there was infiltration of the ciliary body and peripheral choroid and a large uveal effusion. Pain would seem to be a pathognomic sign of metastatic tumor in choroideal detachment caused by metastatic tumor.
Subject(s)
Eye Neoplasms , Neoplasm Metastasis , Uvea , Aged , Humans , Male , Retinal Detachment/etiologyABSTRACT
Retrocorneal membranes can be composed from one layer only -- endothelium, or two layers: endothelium and Descemet, or three layers: endothelium, Descemet membrane and corneal stroma. Besides those corneal membranes which may occur after keratoplasty there are also other forms of inflammatory, degenerative, traumatic or genetic origin. Because diminished corneal transparency often occurs in those cases the precise diagnosis may be difficult on clinical investigation, often only after histological examination the membrane structure may be established.
Subject(s)
Descemet Membrane/pathology , Cataract/complications , Cataract Extraction , Glaucoma/complications , Humans , Keratitis/etiology , Keratitis, Dendritic/pathology , Osteogenesis Imperfecta/genetics , Sclera/abnormalities , SyndromeABSTRACT
In 11 cases of leukaemia or other lymphatic system disease meningeal affection occurred together with an oedema of optic papilla. In 6 patients (9 eyes) visual accuity fell down till 0.1 or worse. By irradiation of retrobulbar spaces in 4 of 5 cases a marked visual accuity improvement was obtained. In 2 other patients an infiltration of optic nerve was found only post mortem through histological examination. In those patients visual accuity was not diminished.
