1.
Arch Gynecol
; 228(1-4): 461-2, 1979 Jul 20.
Article
in German
| MEDLINE
| ID: mdl-573594
Subject(s)
Breast Neoplasms/drug therapy , Animals , Breast Neoplasms/radiotherapy , Female , Humans , Mice , Mice, Nude , Neoplasm Transplantation
2.
Arch Gynecol
; 228(1-4): 455, 1979 Jul 20.
Article
in German
| MEDLINE
| ID: mdl-485434
Subject(s)
Breast Neoplasms/therapy , Immunotherapy , Animals , Antibodies, Neoplasm , Female , Humans , Mice , Mice, Nude , Neoplasm Transplantation
3.
Chir Forum Exp Klin Forsch
; : 175-8, 1979.
Article
in German
| MEDLINE
| ID: mdl-456125
ABSTRACT
Of 150 human breast cancers, 90 (60%) were successfully transplanted onto thymusaplastic nude mice without the use of adjunctive immunosuppressive therapy. Four months after transplantation, 12 rapidly growing tumors had diameters of 2.5-3.5 cm. Investigations revealed a high correlation between the histology of original tumors and xenografts. We conclude that the nude mouse may be used as an animal model for studies such as this, or in determining the sensitivity of transplanted tumors to cytostatic drugs, steroid hormones, and radiation.