ABSTRACT
BACKGROUND: Transnasal evaporative cooling has sufficient heat transfer capacity for effective intra-arrest cooling and improves survival in swine. The aim of this study was to determine the safety, feasibility, and cooling efficacy of prehospital transnasal cooling in humans and to explore its effects on neurologically intact survival to hospital discharge. METHODS AND RESULTS: Witnessed cardiac arrest patients with a treatment interval Subject(s)
Emergency Medical Services/methods
, Heart Arrest/therapy
, Hypothermia, Induced/instrumentation
, Hypothermia, Induced/methods
, Administration, Intranasal
, Aged
, Body Temperature/physiology
, Cold Temperature
, Female
, Heart Arrest/physiopathology
, Humans
, Male
, Middle Aged
, Prospective Studies
, Time Factors
