ABSTRACT
Based on the "membrane" mechanism of biological action of low radiation doses, described earlier, a possible common explanation of radiation and chemical hormesis initiation is proposed.
Subject(s)
Dose-Response Relationship, Drug , Dose-Response Relationship, Radiation , Radiation Dosage , Adaptation, Physiological , Animals , Cell Division/drug effects , Cell Division/radiation effects , Cell Membrane/drug effects , Cell Membrane/metabolism , Cell Membrane/radiation effects , Cells/drug effects , Cells/metabolism , Cells/radiation effects , DNA Damage , DNA Repair , Female , Genes/radiation effects , Humans , Hydrogen-Ion Concentration , Male , Mitogens/pharmacology , Radiation Injuries/genetics , Radiation Injuries/metabolism , Transcription, GeneticABSTRACT
Possible mechanism of superhigh frequency (10(10)-10(12) Hz) electromagnetic oscillation generation by an external proton in a system of hydrogen bonds of biomacromolecules is briefly discussed. The external proton in a proton channel deforms the potential profile of the proton of hydrogen bond in such a way, that there appears a possibility of the low frequency proton tunneling along the hydrogen bond. The interaction with the neighbouring bonds leads to further lowering of the generated frequency.
Subject(s)
Biopolymers , Macromolecular Substances , Protons , Electromagnetic Phenomena , Hydrogen Bonding , Hydrogen-Ion Concentration , Models, BiologicalABSTRACT
Phase transitions in a bicomponent lipid membrane are considered. It is shown that in this case metastable states practically do not arise and phase transitions are smooth and hysteresisless. An elastic frame on the surface of the membrane changes the character of phase transitions: they become sharp and hysteretic. The role of membrane phase transitions for regulation of cell processes is considered.
