[Remodeling in cardiac failure of functional class I due to arterial hypertension associated with ischemic heart disease]. / Remodelirovanie pri serdechnoi nedostatochnosti I funktsional'nogo klassa vsledstvie arterial'noi gipertonii, assotsiirovannoi s ischemicheskoibolezn'iu serdtsa.

Hemodynamics and ventricular remodeling were studied echocardiographically in 192 men with heart failure (NYHA functional class I), arterial hypertension (AH) of stage I-III and clinical picture of ischemic heart disease (IHD). The latter presented in the patients with stable angina pectoris of FC I-II (SAP), unstable angina pectoris (UAP) without foci, paroxysmal atrial fibrillation, acute myocardial infarction (MI), postinfarction cardiosclerosis (PC) with SAP or UAP. The control group consisted of 41 healthy men. The patients had AH stage 1. The patients and healthy controls differed significantly by the size of the aorta, left atrium, thickness of the interventricular septum and posterior wall of the left ventricle. There was a significant left-ventucular hypertrophy in the groups with patients with MI, SAP and PC, UAP and PC (p < 0.001). In these groups the type of left ventricular remodeling was characterized as excentric type of left ventricular hypertrophy without its delatation. Normal left ventricular geometry was in healthy men, SAP, UAP, paroxysmal actual fibrillation.

[Seasonal and circadian rhythms of the excretion of androgens and their fractions in peptic ulcer patients in the remission phase in the markedly continental climate of Transbaikalia]. / Seasonnye i tsirkadnye ritmy ékskretsii androgenov i ikh fraktsii u bol'nykh iazvennoi bolezn'iu v faze remissii v usloviiakh rezko kontinental'nogo klimata Zabaikal'ia.

Seasonal rhythms of androgen excretion were studied in 247 normal subjects and 213 patients with peptic ulcer in the stage of remission. Circadian rhythms were examined in 84 patients and excretion of androgen fractions in 81 patients. The patients manifested changes in the seasonal rhythms of androgen excretion. In winter period, androgen excretion was higher in the patients with peptic ulcer but in spring, the normal subjects had a higher excretion than patients, whereas in summer the patients had a higher excretion than normal subjects. Despite the preservation of the rhythmical pattern the patients demonstrated changes in the rhythm expressed in the decreased amplitude of seasonal fluctuations and deformation of the seasonal rhythm. Circadian rhythms differed only at some seasons. The difference in excretion of androgens (dehydroandrosterone and androsterone) were revealed at individual seasons. Deformation of the rhythms in peptic ulcer patients can be corrected by application of early preventive measures aimed at normalization of the excretory rhythm and restoration of the rhythm characteristic of the regional climatic zone under consideration.