ABSTRACT
A young dog was presented with a history of chronic diarrhea, anorexia, and weight loss. Histoplasma capsulatum was suspected, based on cytologic examination of lymph node aspirates and peritoneal fluid, and confirmed by fungal culture. To our knowledge, this is the first case of histoplasmosis diagnosed in a dog in Atlantic Canada.
Subject(s)
Antifungal Agents/therapeutic use , Dog Diseases/diagnosis , Histoplasma/isolation & purification , Histoplasmosis/veterinary , Animals , Dog Diseases/drug therapy , Dog Diseases/epidemiology , Dogs , Female , Histoplasmosis/diagnosis , Histoplasmosis/drug therapy , Histoplasmosis/epidemiology , New Brunswick/epidemiology , Treatment OutcomeABSTRACT
A 10-year-old, spayed female, Irish water spaniel was presented with a 2-week history of anisocoria characterized by mydriasis of the right eye compared to the left eye in ambient light. Ophthalmic and neurological examinations, combined with pharmacological testing, identified a disease process affecting the right parasympathetic nucleus of cranial nerve 3 (CN III) and/or the parasympathetic component of CN III. Magnetic resonance imaging (MRI) identified a mass involving the right midbrain and extending caudally to the rostral border of the medulla oblongata. The dog became comatose within 12 h following MRI and was euthanized. Histopathology identified the intracranial mass as a meningioma.