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1.
Appl Radiat Isot ; 115: 147-154, 2016 Sep.
Article in English | MEDLINE | ID: mdl-27380197

ABSTRACT

In this paper, we have studied the intensity ratios Kß/Kα depending on the temperature for transition elements Mo, Nb, Zr and Y by 59.5keV γ-rays from a 100 mCi (241)Am radioisotope point source. The Kα and Kß emission spectra of Mo, Nb, Zr and Y were measured by using a Si (Li) solid-state detector at temperature between 40 and 400°C. σKα and σKß production cross-sections, Kß/Kα intensity ratios, asymmetry factor, energy shifts and full width half maximum (FWHM) values of the elements have been calculated. Temperature-dependent changes of the parameters are tabulated and given in the graphical forms. Based on the results obtained, Kß/Kα X-ray intensity ratios of the elements are dependent on the temperature. It is shown that σKß fluorescence cross sections of Mo, Nb and Zr have more increase rate than σKα fluorescence cross sections with increasing temperature. For Y, σKα and σKß production cross-sections firstly decrease, then increase. In general, Kß/Kα X-ray intensity ratios tend to increase with increasing temperature. Some significant shifts are observed in Kα and Kß emission spectra of Mo and Y. These results may contribute to the XRF studies of transition metals.

2.
Int J Radiat Biol ; 92(7): 380-7, 2016 07.
Article in English | MEDLINE | ID: mdl-27124103

ABSTRACT

PURPOSE: Recently, there has been an increase in interest into research into radioprotective agents. Radioprotectors are compounds that protect against radiation injury when given orally (through drinking water) prior to radiation exposure. The purpose is to achieve preferred protection of normal tissues against injury inflicted by ionizing radiation used to treat tumors. The main aim of this work is to investigate energy absorption (EABF) and exposure buildup factors (EBF) of commonly used some radioprotective agents. MATERIALS AND METHODS: We have used the Geometric Progression (G-P) fitting method for calculating the equivalent atomic number (Zeq), for EABF and EBF buildup factors of the radioprotective agents in the energy range 0.015-15 MeV for penetration depths up to 40 mean free path. RESULTS: Significant variations in both EABF and EBF values were observed for several agents at the moderate energy region. At energies below 0.1 MeV, EABF and EBF values increased with decreasing equivalent atomic number Zeq of the samples. At energies >0.15 MeV, EABF and EBF values were found to decrease with decreasing Zeq of all agents. In addition, EABF and EBF were the largest for carnosin, tempol, melatonin, interferon gamma and orientine at 0.05 and 0.06 MeV, respectively, and the minimum values of buildup factors were at 0.1 MeV for cysteine, amifostine, penicillamine and glutathione. CONCLUSIONS: Cysteine and amifostine are good compounds for gamma rays absorption applications among the selected compounds. The presented results in this study are expected to be helpful in radiation dosimetry.


Subject(s)
Absorption, Radiation , Algorithms , Dose-Response Relationship, Radiation , Models, Chemical , Radiation-Protective Agents/chemistry , Radiation-Protective Agents/radiation effects , Computer Simulation , Energy Transfer/radiation effects , Materials Testing , Radiation Dosage
3.
Appl Radiat Isot ; 90: 265-73, 2014 Aug.
Article in English | MEDLINE | ID: mdl-24859334

ABSTRACT

Human radiation exposure is increasing due to radiation development in science and technology. The development of radioprotective agents is important for protecting patients from the side effects of radiotherapy and for protecting the public from unwanted irradiation. Radioprotective agents are used to reduce the damage caused by radiation in healthy tissues. There are several classes of radioprotective compounds that are under investigation. Analgesics and anti-inflammatory compounds are being considered for treating or preventing the effects of damage due to radiation exposure, or for increasing the chance of survival after exposure to a high dose of radiation. In this study, we investigated the radioprotective effects of some analgesic and anti-inflammatory compounds by evaluating buildup factors. The gamma ray energy absorption (EABF) and exposure buildup factors (EBF) were calculated to select compounds in a 0.015-15 MeV energy region up to a penetration depth of 40 mfp (mean free path). Variations of EABF and EBF with incident photon energy and penetration depth elements were also investigated. Significant variations in both EABF and EBF values were observed for several compounds at the moderate energy region. At energies below 0.15 MeV, EABF and EBF values increased with decreasing equivalent atomic number (Z(eq)) of the samples. In addition, EABF and EBF were the largest for ibuprofen, aspirin, paracetamol, naproxen and ketoprofen at 0.05 and 0.06 MeV, respectively, and the EABF value was 0.1 MeV for aceclofenac. From these results, we concluded that the buildup of photons is less for aceclofenac compared to other materials.


Subject(s)
Absorption, Radiation , Anti-Inflammatory Agents/chemistry , Anti-Inflammatory Agents/radiation effects , Models, Chemical , Photons , Radiation-Protective Agents/chemistry , Radiation-Protective Agents/radiation effects , Computer Simulation , Materials Testing
4.
Appl Radiat Isot ; 69(2): 381-8, 2011 Feb.
Article in English | MEDLINE | ID: mdl-21123075

ABSTRACT

Human tissues with endometriosis have been analyzed in terms of energy absorption (EABF) and exposure (EBF) buildup factors using the five-parameter geometric progression (G-P) fitting formula in the energy region 0.015-15 MeV up to a penetration depth of 40 mfp (mean free path). Chemical compositions of the tissue samples were determined using a wavelength dispersive X-ray fluorescence spectrometer (WDXRFS). Possible conclusions were drawn due to significant variations in EABF and EBF for the selected tissues when photon energy, penetration depth and chemical composition changed. Buildup factors so obtained may be of use when the method of choice for treatment of endometriosis is radiotherapy.


Subject(s)
Endometriosis/radiotherapy , Endometrium/radiation effects , Gamma Rays , Radiotherapy Dosage , Body Burden , Female , Humans , Uncertainty
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