1.
Onderstepoort J Vet Res
; 44(3): 151-6, 1977 Sep.
Article
in English
| MEDLINE
| ID: mdl-614532
ABSTRACT
A novel technique, based on cytotoxicity-neutralization, was developed for the in vitro titration of anti-sheep lymphocyte and anti-sheep macrophage sera. The titres obtained for a number of antisera were compared with those found in an agglutination assay. Anti-lymphocyte sera with a high cytotoxicity-neutralization titre very effectively suppressed the number of circulating lymphocytes in the peripheral blood of treated new-born lambs, thus indicating in vivo immunosuppressive activity.
Subject(s)
Animals, Newborn/immunology , Immunosuppression Therapy , Sheep/immunology , Agglutination Tests , Animals , Antilymphocyte Serum/pharmacology , Cyclophosphamide/pharmacology , Cytotoxicity Tests, Immunologic , Immune Sera/pharmacology , Leukocyte Count , Lymphocytes/immunology , Macrophages/immunology , Neutralization Tests
2.
Onderstepoort J Vet Res
; 39(3): 125-31, 1972 Sep.
Article
in English
| MEDLINE
| ID: mdl-4352039